(Q27673277)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22984634%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes (English)

1 reference

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13 February 2020

0 references

0 references

1

1 reference

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13 February 2020

Shu Xu

4

1 reference

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13 February 2020

Surajit Banerjee

8

1 reference

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13 February 2020

Keith A. Sharkey

9

1 reference

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13 February 2020

10

Lawrence J Marnett

1 reference

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13 February 2020

3

Philip J Kingsley

1 reference

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13 February 2020

5

Brenda C Crews

1 reference

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13 February 2020

2

Daniel J Hermanson

1 reference

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13 February 2020

author name string

Winnie Ho

6

1 reference

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13 February 2020

Catherine M Keenan

7

1 reference

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13 February 2020

publication date

15 August 2012

1 reference

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ACS Medicinal Chemistry Letters

13 February 2020

published in

2 references

Crossref

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13 February 2020

volume

3

1 reference

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13 February 2020

issue

9

1 reference

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13 February 2020

page(s)

759-763

1 reference

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(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Prostaglandins and leukotrienes: advances in eicosanoid biology

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Chiral inversion of 2-arylpropionyl-CoA esters by human α-methylacyl-CoA racemase 1A (P504S)--a potential mechanism for the anti-cancer effects of ibuprofen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Biosynthesis and degradation of the endocannabinoid 2-arachidonoylglycerol

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Modulation of the endocannabinoid system: neuroprotection or neurotoxicity?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Ibuprofen: pharmacology, efficacy and safety

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Cyclooxygenases: structural and functional insights

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Loss of cannabinoid receptor 1 accelerates intestinal tumor growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures--a short review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Cyclooxygenase-2: a therapeutic target

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

A double-blind comparison of parenteral morphine, placebo, and oral fenoprofen in management of postoperative pain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

COX-2 oxidative metabolite of endocannabinoid 2-AG enhances excitatory glutamatergic synaptic transmission and induces neurotoxicity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Bioinversion of R-flurbiprofen to S-flurbiprofen at various dose levels in rat, mouse, and monkey

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441040

Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22984634

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential effects of spinal (R)-ketoprofen and (S)-ketoprofen against signs of neuropathic pain and tonic nociception: evidence for a novel mechanism of action of (R)-ketoprofen against tactile allodynia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22984634

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ML3001616

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22984634%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22984634%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22984634

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22984634%20AND%20SRC:MED&resulttype=core&format=json