(Q27674495)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Serine is a natural ligand and allosteric activator of pyruvate kinase M2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

Erratum: Corrigendum: Serine is a natural ligand and allosteric activator of pyruvate kinase M2

10 March 2020

corrigendum / erratum

0 references

author

Petra Hillmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Oliver D K Maddocks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Christian Frezza

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Eyal Gottlieb

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

10

Karen H Vousden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

author name string

Barbara Chaneton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Liang Zheng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Agnès C L Martin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Achuthanunni Chokkathukalam

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Joseph E Coyle

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Andris Jankevics

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Finn P Holding

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Marc O'Reilly

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

language of work or name

English

0 references

publication date

14 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

491

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

issue

7424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

458-462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

Pyruvate kinase M2 is a phosphotyrosine-binding protein

10 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Improved R-factors for diffraction data analysis in macromolecular crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Pyruvate kinase type M2 and its role in tumor growth and spreading

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

A common open representation of mass spectrometry data and its application to proteomics research

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Highly sensitive feature detection for high resolution LC/MS

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Fragment screening using X-ray crystallography.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

PeakML/mzMatch: a file format, Java library, R library, and tool-chain for mass spectrometry data analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Targeting metabolic transformation for cancer therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

ProteoWizard: open source software for rapid proteomics tools development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Automated protein-ligand crystallography for structure-based drug design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

L-serine in disease and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

The allosteric regulation of pyruvate kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Interchange of amino acids between tumor and host

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Nutrient and hormonal regulation of pyruvate kinase gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

Simultaneous determination of multiple intracellular metabolites in glycolysis, pentose phosphate pathway and tricarboxylic acid cycle by liquid chromatography-mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

Structural and kinetic differences between the M2 type pyruvate kinases from lung and various tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3894725

Nitrogen metabolism in tumor bearing mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064226

12 December 2020

inferred from PubMed ID database lookup

Correction of 13C mass isotopomer distributions for natural stable isotope abundance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23064226

12 December 2020

inferred from PubMed ID database lookup

On the use of the merging R factor as a quality indicator for X-ray data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

7 January 2021

inferred from DOI database lookup

Global indicators of X-ray data quality

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11540

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11540

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1000007436

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23064226%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

2 references