(Q27674815)

6

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John A. Tainer

object named as

John A Tainer

15

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author name string

Oliver J Wilkinson

1

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Vitaly Latypov

2

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Julie L Tubbs

3

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Christopher L Millington

4

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Rihito Morita

5

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Andrew Marriott

7

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Gail McGown

8

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Mary Thorncroft

9

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Amanda J Watson

10

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Bernard A Connolly

11

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Jane A Grasby

12

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Ryoji Masui

13

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Christopher A Hunter

14

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Geoffrey P Margison

16

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David M Williams

Proceedings of the National Academy of Sciences of the United States of America

17

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language of work or name

English

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publication date

13 November 2012

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published in

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volume

109

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issue

46

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page(s)

18755-60

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cites work

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20 March 2017

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Structural Basis ofO6-Alkylguanine Recognition by a Bacterial Alkyltransferase-like DNA Repair Protein

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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Flipping of alkylated DNA damage bridges base and nucleotide excision repair

20 March 2017

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Inhibition of O6-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli

20 March 2017

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Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

20 March 2017

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Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

20 March 2017

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Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

20 March 2017

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20 March 2017

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Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products

20 March 2017

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Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli

20 March 2017

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Phasercrystallographic software

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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The Cationminus signpi Interaction

20 March 2017

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Substituent effects on cation- interactions: A quantitative study

20 March 2017

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Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools

24 May 2017

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Alkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O6-alkylguanine adducts in Escherichia coli.

29 September 2017

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Alkyltransferase-like proteins: molecular switches between DNA repair pathways

29 September 2017

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Damage detection and base flipping in direct DNA alkylation repair

29 September 2017

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An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein

29 September 2017

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A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli

29 September 2017

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29 September 2017

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DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy

29 September 2017

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The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

29 September 2017

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A novel DNA damage recognition protein in Schizosaccharomyces pombe

29 September 2017

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DNA-binding mechanism of O6-alkylguanine-DNA alkyltransferase. Effects of protein and DNA alkylation on complex stability

29 September 2017

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O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy

29 September 2017

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Reaction and binding of oligodeoxynucleotides containing analogues of O6-methylguanine with wild-type and mutant human O6-alkylguanine-DNA alkyltransferase

29 September 2017

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Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides

29 September 2017

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Novel synthesis of O6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O6-methylguanine DNA methyltransferase (MGMT).

29 September 2017

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Repair of O6-methylguanine, O6-ethylguanine, O6-isopropylguanine and O4-methylthymine in synthetic oligodeoxynucleotides by Escherichia coli ada gene O6-alkylguanine-DNA-alkyltransferase

2 June 2018

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DNA binding and nucleotide flipping by the human DNA repair protein AGT.

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Differences in the rate of repair of O6-alkylguanines in different sequence contexts by O6-alkylguanine-DNA alkyltransferase

21 January 2018

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Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.

21 January 2018

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Polar, functionalized guanine-O6 derivatives resistant to repair by O6-alkylguanine-DNA alkyltransferase: implications for the design of DNA-modifying drugs.

21 January 2018

1 reference

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The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O(6)-alkylguanine adducts in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1209451109

Role of alkyltransferase-like (ATL) protein in repair of methylated DNA lesions in Thermus thermophilus

21 January 2018

1 reference

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21 January 2018

1 reference

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Convenient and efficient syntheses of oligodeoxyribonucleotides containing O(6)-(carboxymethyl)guanine and O(6)-(4-oxo-4-(3-pyridyl)butyl)guanine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1209451109

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

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Quantifying intermolecular interactions: guidelines for the molecular recognition toolbox

21 January 2018

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12 December 2020

MGMT inhibitors--The Trinity College-Paterson Institute experience, a chemist's perception

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12 December 2020

The role of tyrosine-158 in O6-alkylguanine-DNA alkyltransferase activity

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12 December 2020

Nitrosated glycine derivatives as a potential source of O6-methylguanine in DNA

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12 December 2020

Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases

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12 December 2020