(Q27675909)

1

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Jialin Liu

3

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Michael R Waterman

4

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W David Nes

5

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Galina I Lepesheva

Journal of Lipid Research

6

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publication date

February 2012

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published in

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volume

53

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issue

2

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page(s)

311-20

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cites work

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Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1

20 March 2017

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Structural Insights into Inhibition of Sterol 14 -Demethylase in the Human Pathogen Trypanosoma cruzi

20 March 2017

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Structural basis of human CYP51 inhibition by antifungal azoles

20 March 2017

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Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections

20 March 2017

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Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

20 March 2017

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Pivotal role of water in the mechanism of P450BM-3

20 March 2017

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Phasercrystallographic software

20 March 2017

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REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use

20 March 2017

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Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis

20 March 2017

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Biosynthesis of cholesterol and other sterols

20 March 2017

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Sterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasis

20 March 2017

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Mechanisms of cytochrome P450 substrate oxidation: MiniReview

20 March 2017

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Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways

20 March 2017

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Molecular evolution of biomembranes: structural equivalents and phylogenetic precursors of sterols

20 March 2017

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

20 March 2017

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A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

7 April 2017

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Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51)

7 April 2017

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Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics

29 September 2017

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Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib

29 September 2017

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Structural basis for conservation in the CYP51 family

29 September 2017

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Sterol biosynthesis and prokaryotes-to-eukaryotes evolution

29 September 2017

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Biodiversity of CYP51 in trypanosomes

29 September 2017

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Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms

29 September 2017

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Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity

29 September 2017

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Active site mapping and substrate channeling in the sterol methyltransferase pathway

29 September 2017

1 reference

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Uncommon P450-catalyzed reactions

29 September 2017

1 reference

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Cytochrome P450 and the individuality of species

29 September 2017

1 reference

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Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species

29 September 2017

1 reference

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Sterol structure and membrane function

29 September 2017

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32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis

29 September 2017

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Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis

2 June 2018

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Cytochrome P-450 heme moiety. The specific target in drug-induced heme alkylation

2 June 2018

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Sterol, Structure and Membrane Function

2 June 2018

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CYP51 from Trypanosoma brucei is obtusifoliol-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M021865

CYP51 from Trypanosoma cruzi: a phyla-specific residue in the B' helix defines substrate preferences of sterol 14alpha-demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M021865

Photoaffinity labeling of the N-methyltransferase domains of cyclosporin synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M021865

Benzylic oxidation of gemfibrozil-1-O-beta-glucuronide by P450 2C8 leads to heme alkylation and irreversible inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M021865

Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M021865

The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450).

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M021865

Modified acetylenic steroids as potent mechanism-based inhibitors of cytochrome P-450SCC

21 January 2018

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12 December 2020

Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase

1 reference

12 December 2020

Synthesis and antifungal properties of 14-aminomethyl-substituted lanosterol derivatives

1 reference

12 December 2020

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences

1 reference

12 December 2020

Destruction of cytochrome P-450 by ethylene and other olefins

1 reference

12 December 2020

Mechanism-based enzyme inactivators

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12 December 2020

Mechanism-based inhibition of rat liver microsomal diazepam C3-hydroxylase by mifepristone associated with loss of spectrally detectable cytochrome P450

1 reference

12 December 2020

Oxidation of 17 alpha-ethynylestradiol by human liver cytochrome P-450

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12 December 2020

Substrate-based inhibitors of lanosterol 14 alpha-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties

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12 December 2020

Sterol synthesis. A simplified method for the synthesis of 32-oxygenated derivatives of 24,25-dihydrolanosterol

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12 December 2020