(Q27675971)

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Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex

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Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex (English)

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Fergus J. Couch

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Fergus J Couch

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author name string

Namit Singh

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Timothy D Wiltshire

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James R Thompson

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Georges Mer

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language of work or name

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publication date

20 January 2012

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Journal of Biological Chemistry

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287

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4

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2854-62

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BRCT domains: easy as one, two, three

1 reference

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20 March 2017

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20 March 2017

Systematic analysis of human protein complexes identifies chromosome segregation proteins

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20 March 2017

Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1

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20 March 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

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20 March 2017

γH2A binds Brc1 to maintain genome integrity during S-phase

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20 March 2017

Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair

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20 March 2017

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

1 reference

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20 March 2017

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

1 reference

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20 March 2017

Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains

1 reference

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20 March 2017

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

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20 March 2017

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

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20 March 2017

Multiple tumor suppressor pathways negatively regulate telomerase

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20 March 2017

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

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20 March 2017

Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

1 reference

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20 March 2017

Phasercrystallographic software

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

The finer things in X-ray diffraction data collection

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

The DNA damage response mediator MDC1 directly interacts with the anaphase-promoting complex/cyclosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

20 March 2017

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

1 reference

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7 April 2017

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

1 reference

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7 April 2017

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

7 April 2017

Structural basis for the subunit assembly of the anaphase-promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair

1 reference

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29 September 2017

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus formation and centrosomal localization.

1 reference

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29 September 2017

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

A computational method for the analysis and prediction of protein:phosphopeptide-binding sites.

1 reference

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29 September 2017

Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

29 September 2017

BRIT1/MCPH1 is a multifunctional DNA damage responsive protein mediating DNA repair-associated chromatin remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268443

2 June 2018

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307868

21 January 2018

Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.307868

21 January 2018

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21 January 2018

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