(Q40265990)

19 September 2017

Regulation of mitotic entry by microcephalin and its overlap with ATR signalling (English)

1 reference

19 September 2017

Mark O'Driscoll

8

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Gemma K. Alderton

object named as

Gemma K Alderton

1

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Andrew Jackson

object named as

Andrew P Jackson

6

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Heidemarie Neitzel

5

object named as

Heidemarie Neitzel

1 reference

19 September 2017

Laura Galbiati

2

1 reference

19 September 2017

Elen Griffith

3

1 reference

19 September 2017

Katharina H Surinya

4

1 reference

19 September 2017

Penny A Jeggo

7

1 reference

19 September 2017

18 June 2006

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19 September 2017

1 reference

19 September 2017

8

1 reference

19 September 2017

725-733

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19 September 2017

7

1 reference

https://scigraph.springernature.com/pub.10.1038/ncb1431

19 September 2017

0 references

cites work

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

1 reference

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

21 January 2018

1 reference

Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings

21 January 2018

1 reference

Identification of microcephalin, a protein implicated in determining the size of the human brain

21 January 2018

1 reference

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

21 January 2018

1 reference

Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway.

21 January 2018

1 reference

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 January 2018

1 reference

ATM and ATR: networking cellular responses to DNA damage

21 January 2018

1 reference

H2AX: the histone guardian of the genome

21 January 2018

1 reference

Nbs1 is required for ATR-dependent phosphorylation events

21 January 2018

1 reference

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

21 January 2018

1 reference

Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.

21 January 2018

1 reference

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

21 January 2018

1 reference

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

1 reference

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

21 January 2018

1 reference

Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability

21 January 2018

1 reference

Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding

21 January 2018

1 reference

Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism

21 January 2018

1 reference

ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage

21 January 2018

1 reference

Regulating mammalian checkpoints through Cdc25 inactivation

21 January 2018

1 reference

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage.

21 January 2018

1 reference

DNA replication in eukaryotic cells

21 January 2018

1 reference

DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p

21 January 2018

1 reference

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

21 January 2018

1 reference

Misreading of termination codons in eukaryotes by natural nonsense suppressor tRNAs

21 January 2018

1 reference

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 January 2018

1 reference

MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation

21 January 2018

1 reference

Mutations in microcephalin cause aberrant regulation of chromosome condensation.

21 January 2018

1 reference

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

21 January 2018

1 reference

Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1431

1 reference

19 September 2017

1 reference