(Q27677475)

6

1 reference

ORCID Public Data File 2021

Irene T Weber

7

object named as

Irene T Weber

0 references

author name string

Arun K Ghosh

1

0 references

Bruno D Chapsal

2

0 references

Melinda Steffey

3

0 references

Yuan-Fang Wang

5

0 references

Hiroaki Mitsuya

Bioorganic & Medicinal Chemistry Letters

8

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language of work or name

English

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publication date

15 March 2012

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published in

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volume

22

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issue

6

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page(s)

2308-11

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cites work

Design of HIV-1 Protease Inhibitors with C3-Substituted Hexahydrocyclopentafuranyl Urethanes as P2-Ligands: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

1 reference

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Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters

20 March 2017

1 reference

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Design of HIV-1 Protease Inhibitors with Pyrrolidinones and Oxazolidinones as Novel P1′-Ligands To Enhance Backbone-Binding Interactions with Protease: Synthesis, Biological Evaluation, and Protein−Ligand X-ray Studies ∞

20 March 2017

1 reference

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Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV

20 March 2017

1 reference

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Structural implications of drug-resistant mutants of HIV-1 protease: high-resolution crystal structures of the mutant protease/substrate analogue complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

A graphical user interface to the CCP4 program suite

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Harnessing nature's insight: design of aspartyl protease inhibitors from treatment of drug-resistant HIV to Alzheimer's disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Design and synthesis of stereochemically defined novel spirocyclic P2-ligands for HIV-1 protease inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114

29 September 2017

1 reference

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Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance

29 September 2017

1 reference

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Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro.

29 September 2017

1 reference

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A simple, continuous fluorometric assay for HIV protease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433276

Demonstration of sustained drug-resistant human immunodeficiency virus type 1 lineages circulating among treatment-naïve individuals

2 June 2018

1 reference

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Antiretroviral-drug resistance among patients recently infected with HIV.

27 November 2018

1 reference

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Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22364812