(Q27677532)

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Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22374650%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations (English)

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Europe PubMed Central

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24 January 2020

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24 January 2020

Gerd Buntkowsky

8

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Gerd Buntkowsky

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24 January 2020

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Marco Tischler

1

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24 January 2020

Daichi Nasu

2

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24 January 2020

Martin Empting

3

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24 January 2020

Stefan Schmelz

4

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24 January 2020

Dirk W Heinz

5

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24 January 2020

Philipp Rottmann

6

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24 January 2020

Harald Kolmar

7

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24 January 2020

Olga Avrutina

10

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24 January 2020

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28 February 2012

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24 January 2020

Angewandte Chemie International Edition

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24 January 2020

51

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24 January 2020

15

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24 January 2020

3708-3712

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24 January 2020

Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information.

1 reference

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21 January 2018

Non-proline cis peptide bonds in proteins.

1 reference

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21 January 2018

Occurrence and role of cis peptide bonds in protein structures

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Peptide bonds revisited

1 reference

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Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.

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Extraction of consensus protein patterns in regions containing non-proline cis peptide bonds and their functional assessment

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Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation

1 reference

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21 January 2018

Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates

1 reference

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21 January 2018

A case study of 2,2-dimethylthiazolidine as locked cis proline amide bond: synthesis, NMR and molecular modeling studies of a delta-conotoxin EVIA peptide analog

1 reference

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21 January 2018

Prolyl cis-trans isomerization as a molecular timer

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Impact of cis-proline analogs on peptide conformation

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

cis-peptide bond mimetic tetrazole analogs of the insect kinins identify the active conformation

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

A cis amide bond surrogate incorporating 1,2,4-triazole

1 reference

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21 January 2018

Development of a functional cis-prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase.

1 reference

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21 January 2018

Semisynthesis of proteins by expressed protein ligation

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21 January 2018

"Clicktophycin-52": a bioactive cryptophycin-52 triazole analogue

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21 January 2018

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

1 reference

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21 January 2018

Bowman-Birk inhibitors from legumes and human gastrointestinal health: current status and perspectives.

1 reference

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21 January 2018

The role of threonine in the P2 position of Bowman-Birk proteinase inhibitors: studies on P2 variation in cyclic peptides encompassing the reactive site loop

1 reference

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21 January 2018

Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1.

1 reference

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21 January 2018

Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide

1 reference

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21 January 2018

Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Sunflower trypsin inhibitor-1.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Introduction of the new dipeptide isostere 7-endo-BtA as reverse turn inducer in a Bowman-Birk proteinase inhibitor: synthesis and conformational analysis.

1 reference

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21 January 2018

Improved solid-phase peptide synthesis method utilizing alpha-azide-protected amino acids.

1 reference

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21 January 2018

Maintaining biological activity by using triazoles as disulfide bond mimetics

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21 January 2018

Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism

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21 January 2018

High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds

1 reference

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21 January 2018

Multifunctional "clickates" as versatile extended heteroaromatic building blocks: efficient synthesis via click chemistry, conformational preferences, and metal coordination.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201108983

21 January 2018

Resisting degradation by human elastase: commonality of design features shared by 'canonical' plant and bacterial macrocyclic protease inhibitor scaffolds

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21 January 2018

Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors

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Parallel pathways in the folding of a short-term denatured scFv fragment of an antibody

1 reference

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Enhancing the Proline Effect: Pseudo-Prolines for TailoringCis/TransIsomerization

1 reference

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21 January 2018

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