(Q27677865)

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Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template

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scholarly article

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Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template (English)

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1 reference

based on heuristic

inferred from title

click chemistry

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based on heuristic

inferred from title

Karl Barry Sharpless

10

object named as

K Barry Sharpless

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Valery V. Fokin

12

object named as

Valery V Fokin

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Joseph R Fotsing

3

object named as

Joseph R Fotsing

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4

object named as

Timo Weide

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author name string

Neil P Grimster

1

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Bernhard Stump

2

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Todd T Talley

5

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John G Yamauchi

6

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Ákos Nemecz

7

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Choel Kim

8

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Kwok-Yiu Ho

9

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Palmer Taylor

11

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language of work or name

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publication date

18 April 2012

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Journal of the American Chemical Society

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134

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15

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6732-40

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Creating an 7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein: CRYSTALLOGRAPHIC AND LIGAND SELECTIVITY ANALYSES

1 reference

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20 March 2017

Conformational Remodeling of Femtomolar Inhibitor−Acetylcholinesterase Complexes in the Crystalline State

1 reference

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20 March 2017

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

1 reference

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20 March 2017

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

1 reference

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20 March 2017

Nicotine binding to brain receptors requires a strong cation-pi interaction

1 reference

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20 March 2017

Atomic interactions of neonicotinoid agonists with AChBP: Molecular recognition of the distinctive electronegative pharmacophore

1 reference

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20 March 2017

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

1 reference

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20 March 2017

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

1 reference

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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20 March 2017

Likelihood-enhanced fast rotation functions

1 reference

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20 March 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

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1 reference

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20 March 2017

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

1 reference

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20 March 2017

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

1 reference

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1 reference

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29 September 2017

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

1 reference

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29 September 2017

In situ click chemistry: probing the binding landscapes of biological molecules

1 reference

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29 September 2017

Identification and functional characterization of a novel acetylcholine-binding protein from the marine annelid Capitella teleta

1 reference

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29 September 2017

Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism

1 reference

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29 September 2017

Peptidomimetics via copper-catalyzed azide-alkyne cycloadditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618991

29 September 2017

Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618991

29 September 2017

Ruthenium-catalyzed cycloaddition of alkynes and organic azides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618991

29 September 2017

Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides

1 reference

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29 September 2017

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618991

29 September 2017

Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618991

29 September 2017

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

1 reference

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Supramolecular templating in thermodynamically controlled synthesis

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29 September 2017

Emerging structure of the nicotinic acetylcholine receptors

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2 June 2018

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27 November 2018

Nicotinic receptors, allosteric proteins and medicine.

1 reference

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27 November 2018

In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.

1 reference

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27 November 2018

A heterocyclic peptide nanotube

1 reference

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27 November 2018

A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

1 reference

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27 November 2018

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes.

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Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks

1 reference

https://pubmed.ncbi.nlm.nih.gov/22394239

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Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/22394239

12 December 2020

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inferred from PubMed ID database lookup

Inhibitors of HIV-1 protease by using in situ click chemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22394239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/22394239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA3001858

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