(Q27677946)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

main subject

protein design

0 references

computational biology

1 reference

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Sen Liu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Amelie Stein

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Attila Remenyi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

James S Fraser

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Gregory T Kapp

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Derek T Wong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Brian J Yeh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jack Taunton

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Wendell A Lim

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

language of work or name

English

0 references

publication date

7 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

5277-5282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Following evolutionary paths to protein-protein interactions with high affinity and selectivity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Spatiotemporal control of cell signalling using a light-switchable protein interaction.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

A genetically encoded photoactivatable Rac controls the motility of living cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Rho GTPases in cell biology

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Construction of a genetic toggle switch in Escherichia coli

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Oncogene ect2 is related to regulators of small GTP-binding proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Sub-angstrom accuracy in protein loop reconstruction by robotics-inspired conformational sampling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Predicting the tolerated sequences for proteins and protein interfaces using RosettaBackrub flexible backbone design

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

A simple physical model for binding energy hot spots in protein-protein complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

A synthetic oscillatory network of transcriptional regulators

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Algorithm discovery by protein folding game players

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Rapid diversification of cell signaling phenotypes by modular domain recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Computational design of second-site suppressor mutations at protein-protein interfaces

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Computer-aided design of functional protein interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Design of protein-interaction specificity gives selective bZIP-binding peptides.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

On the Rho'd: the regulation of membrane protrusions by Rho-GTPases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Reconstruction of genetic circuits

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Human RAS superfamily proteins and related GTPases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Reprogramming control of an allosteric signaling switch through modular recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Review: protein design--where we were, where we are, where we're going.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325720

Computational redesign of protein-protein interaction specificity.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114487109

Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114487109

Structure-based prediction of the peptide sequence space recognized by natural and synthetic PDZ domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114487109

A Cdc42 mutant specifically activated by intersectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1114487109

Chronicles of the GTPase switch

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22403064

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1114487109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

ADS bibcode

2012PNAS..109.5277K

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22403064%20AND%20SRC:MED&resulttype=core&format=json