(Q27678314)

4

object named as

Tzu-Ping Ko

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author name string

Chia-I Liu

1

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Wen-Yih Jeng

2

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Wei-Jung Chang

Journal of Biological Chemistry

3

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language of work or name

English

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publication date

25 May 2012

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published in

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volume

287

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issue

22

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page(s)

18750-7

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cites work

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Inhibition of Staphyloxanthin Virulence Factor Biosynthesis in Staphylococcus aureus : In Vitro, in Vivo, and Crystallographic Results †

20 March 2017

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A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence

20 March 2017

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Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress

20 March 2017

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Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

20 March 2017

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Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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20 March 2017

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Macromolecular TLS refinement in REFMAC at moderate resolutions

20 March 2017

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Structure validation by Calpha geometry: phi,psi and Cbeta deviation

20 March 2017

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Structure and regulation of mammalian squalene synthase

20 March 2017

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Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway

20 March 2017

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Squalene synthase inhibitors : clinical pharmacology and cholesterol-lowering potential

20 March 2017

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Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase

20 March 2017

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Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase

20 March 2017

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Natural products as sources of new drugs over the last 25 years

20 March 2017

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Functional microdomains in bacterial membranes

7 April 2017

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Advancing therapy for hypercholesterolemia

29 September 2017

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Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs

29 September 2017

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Cholesterol biosynthesis modulation regulates dengue viral replication

29 September 2017

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Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

29 September 2017

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Squalestatin cures prion-infected neurons and protects against prion neurotoxicity.

29 September 2017

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29 September 2017

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Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus

29 September 2017

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Truncation of human squalene synthase yields active, crystallizable protein

2 June 2018

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Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives

2 June 2018

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Squalestatin protects neurons and reduces the activation of cytoplasmic phospholipase A2 by Abeta(1-42).

2 June 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Novel approach to the zaragozic acids. Enantioselective total synthesis of 6,7-dideoxysqualestatin H5.

21 January 2018

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Identification of novel mammalian squalene synthase inhibitors using a three-dimensional pharmacophore

21 January 2018

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A general access to zaragozic acids: total synthesis and structure elucidation of zaragozic acid D and formal syntheses of zaragozic acids A and C

21 January 2018

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12 December 2020

The squalestatins: novel inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C1-modified analogues

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12 December 2020

Selective protection and relative importance of the carboxylic acid groups of zaragozic acid A for squalene synthase inhibition

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12 December 2020

The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors

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12 December 2020

The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues

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12 December 2020

Viridiofungins, novel inhibitors of sphingolipid synthesis

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12 December 2020