(Q27679153)

7

object named as

Brian K Kobilka

0 references

Aashish Manglik

2

object named as

Aashish Manglik

0 references

Tong Sun Kobilka

4

object named as

Tong Sun Kobilka

0 references

author name string

Sébastien Granier

1

0 references

Andrew C Kruse

3

0 references

Foon Sun Thian

Structure of the human κ-opioid receptor in complex with JDTic

5

0 references

language of work or name

English

0 references

publication date

16 May 2012

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published in

Nature

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volume

485

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page(s)

400-4

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issue

7398

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Peptides as receptor selectivity modulators of opiate pharmacophores

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

The delta opioid receptor: an evolving target for the treatment of brain disorders

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Recent advances in selective opioid receptor agonists and antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Investigation of the selectivity of oxymorphone- and naltrexone-derived ligands via site-directed mutagenesis of opioid receptors: exploring the "address" recognition locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Novel "restoration of function" mutagenesis strategy to identify amino acids of the delta-opioid receptor involved in ligand binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Molecular pharmacology of the opioid receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Specific receptor for the opioid peptide dynorphin: structure--activity relationships

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Application of the message-address concept in the design of highly potent and selective non-peptide delta opioid receptor antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11111

Creating a functional opioid alkaloid binding site in the orphanin FQ receptor through site-directed mutagenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523198

27 November 2018

Identifiers

DOI

10.1038/NATURE11111

1 reference

Dimensions Publication ID

5006027

1016383249

0 references

5006027

1 reference

1 reference

1 reference