(Q27680650)

1

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Hiroyuki Kumeta

2

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Kenji Funami

3

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Masataka Horiuchi

4

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Joy Sarmiento

5

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Kazuo Yamashita

6

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Daron M Standley

7

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Misako Matsumoto

8

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Tsukasa Seya

Proceedings of the National Academy of Sciences of the United States of America

9

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language of work or name

English

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publication date

3 December 2013

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published in

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volume

110

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issue

49

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page(s)

19908-13

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cites work

Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure

1 reference

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Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling

20 March 2017

1 reference

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Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

20 March 2017

1 reference

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Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation

20 March 2017

1 reference

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What the Myddosome structure tells us about the initiation of innate immunity

20 March 2017

1 reference

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Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

20 March 2017

1 reference

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The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants

20 March 2017

1 reference

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Molecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAIN

20 March 2017

1 reference

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Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

20 March 2017

1 reference

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The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer

20 March 2017

1 reference

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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

20 March 2017

1 reference

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

20 March 2017

1 reference

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An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2

20 March 2017

1 reference

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Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

20 March 2017

1 reference

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Pattern recognition receptors and inflammation

20 March 2017

1 reference

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DaliLite workbench for protein structure comparison

20 March 2017

1 reference

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

20 March 2017

1 reference

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The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.

20 March 2017

1 reference

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The death-fold superfamily of homotypic interaction motifs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Homo-oligomerization is essential for Toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-kappaB and interferon regulatory factor-3 activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Structure and function of Toll receptors and their ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

TICAM-1 and TICAM-2: toll-like receptor adapters that participate in induction of type 1 interferons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

TIR domain-containing adaptors define the specificity of TLR signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

MATRAS: A program for protein 3D structure comparison

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Protein structure comparison using the markov transition model of evolution.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Toll-like receptors as molecular switches.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856793

Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1222811110