(Q41229308)

English

Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.

scientific article published on 2 December 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4. (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

toll-like receptor

0 references

5

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

author name string

Celia Bovijn

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Peter Ulrichts

2

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Anne-Sophie De Smet

3

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Dominiek Catteeuw

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Jan Tavernier

6

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Europe PubMed Central

PMC publication ID

28 September 2017

Frank Peelman

7

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Europe PubMed Central

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28 September 2017

language of work or name

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publication date

2 December 2011

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Europe PubMed Central

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28 September 2017

number of pages

11

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

28 September 2017

287

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

4088-4098

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

1 reference

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What the Myddosome structure tells us about the initiation of innate immunity

1 reference

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

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Targeting Toll-like receptors: emerging therapeutics?

1 reference

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28 September 2017

Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site

1 reference

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Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression

1 reference

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Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

1 reference

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28 September 2017

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

TIR-containing adaptors in Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling

1 reference

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MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells

1 reference

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Protein structure modeling with MODELLER

1 reference

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28 September 2017

The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer

1 reference

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28 September 2017

LPS/TLR4 signal transduction pathway

1 reference

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28 September 2017

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Structure and function of Toll receptors and their ligands

1 reference

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28 September 2017

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

1 reference

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28 September 2017

MAPPIT analysis of TLR adaptor complexes

1 reference

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Functional cross-modulation between SOCS proteins can stimulate cytokine signaling

1 reference

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Structural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signaling

1 reference

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28 September 2017

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Binding specificity of Toll-like receptor cytoplasmic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

MAFFT version 5: improvement in accuracy of multiple sequence alignment

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

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Mapping of the leptin binding sites and design of a leptin antagonist

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28 September 2017

Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281722

28 September 2017

An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2

1 reference

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Design and application of a cytokine-receptor-based interaction trap

1 reference

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28 September 2017

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

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28 September 2017

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

1 reference

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1 reference

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1 reference

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Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B

1 reference

https://pubmed.ncbi.nlm.nih.gov/22139835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/22139835

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.282350

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

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