(Q27681111)

2

Franz Y

Ho

1 reference

19 October 2023

Ingrid R Vetter

3

Ingrid R

Vetter

1 reference

19 October 2023

Peter J M van Haastert

4

Peter J M

van Haastert

1 reference

19 October 2023

Arjan Kortholt

6

Arjan

Proceedings of the National Academy of Sciences of the United States of America

Kortholt

1 reference

19 October 2023

language of work or name

English

0 references

publication date

26 June 2012

0 references

published in

0 references

volume

109

0 references

issue

26

0 references

page(s)

10322-7

0 references

cites work

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Structure of the Roc–COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase

20 March 2017

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The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation

20 March 2017

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Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

20 March 2017

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Kinase activity of mutant LRRK2 mediates neuronal toxicity

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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

20 March 2017

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Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

20 March 2017

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Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

7 April 2017

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Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

7 April 2017

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Protein kinases: evolution of dynamic regulatory proteins

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Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2.

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The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

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Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2

29 September 2017

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Parkinson's disease: insights from pathways

29 September 2017

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Characterization of the Roco protein family in Dictyostelium discoideum

29 September 2017

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LRRK2 in Parkinson's disease: biochemical functions

29 September 2017

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Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease

29 September 2017

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29 September 2017

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It takes two to tango: regulation of G proteins by dimerization

29 September 2017

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29 September 2017

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Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition

29 September 2017

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Roc, a Ras/GTPase domain in complex proteins

29 September 2017

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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

29 September 2017

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Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis

29 September 2017

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Intramolecular activation mechanism of the Dictyostelium LRRK2 homolog Roco protein GbpC.

2 June 2018

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Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays.

2 June 2018

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Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation

27 November 2018

1 reference

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Clinical features of LRRK2-associated Parkinson's disease in central Norway

27 November 2018

1 reference

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Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.

27 November 2018

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