(Q27681761)

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Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 June 2017

Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex (English)

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Europe PubMed Central

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25 June 2017

structural biology

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Jacob Lauwring Andersen

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531479%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Søren Skou Thirup

23

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5 June 2020

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Tenna Juul Schrøder

2

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5 June 2020

Søren Christensen

3

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5 June 2020

Dorthe Strandbygård

4

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5 June 2020

Lone Tjener Pallesen

5

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5 June 2020

Maria Marta García-Alai

6

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5 June 2020

Samsa Lindberg

7

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5 June 2020

Morten Langgård

8

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5 June 2020

Jørgen Calí Eskildsen

9

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5 June 2020

Laurent David

10

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5 June 2020

Lena Tagmose

11

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5 June 2020

Klaus Baek Simonsen

12

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5 June 2020

Philip James Maltas

13

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5 June 2020

Lars Christian Biilmann Rønn

14

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5 June 2020

Inge E M de Jong

15

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5 June 2020

Ibrahim John Malik

16

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5 June 2020

Jan Egebjerg

17

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5 June 2020

Jens-Jacob Karlsson

18

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5 June 2020

Srinivas Uppalanchi

19

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5 June 2020

Durga Rao Sakumudi

20

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5 June 2020

Pradheep Eradi

21

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5 June 2020

Steven P Watson

22

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5 June 2020

language of work or name

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publication date

29 January 2014

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25 June 2017

Acta Crystallographica Section D: Biological Crystallography

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5 June 2020

70

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5 June 2020

Pt 2

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5 June 2020

451-460

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5 June 2020

Structure of the agonist-bound neurotensin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Crystal structure of the sodium–potassium pump

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Overview of the CCP4 suite and current developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Features and development of Coot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Phasercrystallographic software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Regulation of cell survival by secreted proneurotrophins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Neurotrophins and their receptors stimulate melanoma cell proliferation and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

20 March 2017

LigPlot+: multiple ligand-protein interaction diagrams for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

7 April 2017

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

7 April 2017

Sequence and structural analysis of the Asp-box motif and Asp-box beta-propellers; a widespread propeller-type characteristic of the Vps10 domain family and several glycoside hydrolase families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

29 September 2017

Proneurotrophin-3 may induce Sortilin-dependent death in inner ear neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

2 June 2018

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

2 June 2018

Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

2 June 2018

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940197

2 June 2018

Mimer: an automated spreadsheet-based crystallization screening system

1 reference

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21 January 2018

Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.

1 reference

https://api.crossref.org/works/10.1107%2FS1399004713030149

21 January 2018

The nature of .pi.-.pi. interactions

1 reference

https://api.crossref.org/works/10.1107%2FS1399004713030149

21 January 2018

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

1 reference

https://api.crossref.org/works/10.1107%2FS1399004713030149

21 January 2018

The yin and yang of neurotrophin action

1 reference

https://api.crossref.org/works/10.1107%2FS1399004713030149

21 January 2018

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1 reference

https://api.crossref.org/works/10.1107%2FS1399004713030149

21 January 2018

Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord.

1 reference

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27 November 2018

Identifiers

10.1107/S1399004713030149

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531479%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531479%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24531479%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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