(Q27682443)

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The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24663151%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

The 2.1 Å resolution structure of cyanopindolol-bound β1-adrenoceptor identifies an intramembrane Na+ ion that stabilises the ligand-free receptor (English)

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12 March 2020

Jennifer L Miller

1

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12 March 2020

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12 March 2020

Gebhard Schertler

5

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12 March 2020

Christopher G. Tate

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12 March 2020

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Rony Nehmé

2

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12 March 2020

Patricia C Edwards

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12 March 2020

Andrew G W Leslie

6

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12 March 2020

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24 March 2014

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12 March 2020

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12 March 2020

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12 March 2020

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12 March 2020

e92727

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12 March 2020

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Creative Commons Attribution 4.0 International

24 March 2014

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High-resolution crystal structure of human protease-activated receptor 1

1 reference

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Structure of the agonist-bound neurotensin receptor

1 reference

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Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

1 reference

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Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol

1 reference

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1 reference

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Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

1 reference

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20 March 2017

Crystal structure of the β2 adrenergic receptor-Gs protein complex

1 reference

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20 March 2017

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

1 reference

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Two distinct conformations of helix 6 observed in antagonist-bound structures of a 1-adrenergic receptor

1 reference

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20 March 2017

Structure of an agonist-bound human A2A adenosine receptor

1 reference

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20 March 2017

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

1 reference

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Structure and function of an irreversible agonist-β(2) adrenoceptor complex

1 reference

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20 March 2017

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

1 reference

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20 March 2017

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

1 reference

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20 March 2017

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

1 reference

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20 March 2017

Structure of a beta1-adrenergic G-protein-coupled receptor

1 reference

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20 March 2017

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

1 reference

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20 March 2017

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

1 reference

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20 March 2017

A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

Phasercrystallographic software

1 reference

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20 March 2017

Scaling and assessment of data quality

1 reference

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20 March 2017

The integration of macromolecular diffraction data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

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Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

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20 March 2017

Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor

1 reference

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20 March 2017

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

Site-directed mutagenesis and continuous expression of human beta-adrenergic receptors. Identification of a conserved aspartate residue involved in agonist binding and receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

20 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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7 April 2017

The structure and function of G-protein-coupled receptors

1 reference

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7 April 2017

Crystallizing membrane proteins using lipidic mesophases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

7 April 2017

Molecular signatures of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3963952

29 September 2017

The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands

1 reference

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29 September 2017

Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination

1 reference

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Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes

1 reference

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Agonist-bound structures of G protein-coupled receptors

1 reference

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29 September 2017

New insights from structural biology into the druggability of G protein-coupled receptors.

1 reference

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1 reference

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Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

1 reference

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Hyponatremia: mechanisms and newer treatments

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1 reference

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29 September 2017

Thermostabilization of the neurotensin receptor NTS1.

1 reference

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1 reference

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1 reference

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29 September 2017

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24663151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium

1 reference

https://pubmed.ncbi.nlm.nih.gov/24663151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association

1 reference

https://pubmed.ncbi.nlm.nih.gov/24663151

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24663151

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based on heuristic

inferred from PubMed ID database lookup

Allosteric modulation of A2A adenosine receptors by amiloride analogues and sodium ions

1 reference

https://pubmed.ncbi.nlm.nih.gov/24663151

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0092727

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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12 March 2020

2014PLoSO...992727M

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24663151%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24663151%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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