(Q34327700)

1 August 2017

title

Molecular signatures of G-protein-coupled receptors (English)

1 reference

G protein-coupled receptor

1 August 2017

main subject

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Xavier Deupi

2

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Gebhard Schertler

object named as

Gebhard F Schertler

5

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Christopher G. Tate

object named as

Christopher G Tate

4

0 references

Mohan Madan Babu

6

object named as

M Madan Babu

1 reference

1 August 2017

A J Venkatakrishnan

1

1 reference

1 August 2017

Guillaume Lebon

3

1 reference

1 August 2017

language of work or name

English

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publication date

1 February 2013

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1 August 2017

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1 August 2017

volume

494

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1 August 2017

issue

7436

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1 August 2017

page(s)

185-194

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

1 August 2017

cites work

1 reference

12 December 2020

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

1 reference

12 December 2020

Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors

1 reference

12 December 2020

Lifting the lid on GPCRs: the role of extracellular loops

1 reference

12 December 2020

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

1 reference

12 December 2020

The role of conformational ensembles of seven transmembrane receptors in functional selectivity

1 reference

12 December 2020

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

1 reference

12 December 2020

The structure and function of G-protein-coupled receptors

1 reference

12 December 2020

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

1 reference

12 December 2020

Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol

1 reference

12 December 2020

Structure and dynamics of the M3 muscarinic acetylcholine receptor

1 reference

12 December 2020

Structural biology. Versatility from protein disorder

1 reference

12 December 2020

Crystal structure of the ligand-free G-protein-coupled receptor opsin

1 reference

12 December 2020

High-resolution crystal structure of human protease-activated receptor 1

1 reference

12 December 2020

Agonist-bound structures of G protein-coupled receptors

1 reference

12 December 2020

Structure of the chemokine receptor CXCR1 in phospholipid bilayers

1 reference

12 December 2020

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

1 reference

12 December 2020

The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors

1 reference

12 December 2020

A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor

1 reference

12 December 2020

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

1 reference

12 December 2020

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

1 reference

12 December 2020

Prediction of membrane protein structures with complex topologies using limited constraints

1 reference

12 December 2020

Structure of the human histamine H1 receptor complex with doxepin

1 reference

12 December 2020

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

1 reference

12 December 2020

Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

1 reference

12 December 2020

Crystal structure of metarhodopsin II

1 reference

12 December 2020

Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

1 reference

12 December 2020

Tracking G-protein-coupled receptor activation using genetically encoded infrared probes.

1 reference

12 December 2020

Escaping the flatlands: new approaches for studying the dynamic assembly and activation of GPCR signaling complexes.

1 reference

12 December 2020

Ligand-induced modulation of the free-energy landscape of G protein-coupled receptors explored by adaptive biasing techniques

1 reference

12 December 2020

Domain coupling in GPCRs: the engine for induced conformational changes

1 reference

12 December 2020

Structure of a beta1-adrenergic G-protein-coupled receptor

1 reference

12 December 2020

Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

1 reference

12 December 2020

The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor

1 reference

12 December 2020

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

12 December 2020

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

1 reference

12 December 2020

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

1 reference

12 December 2020

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

1 reference

12 December 2020

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

1 reference

12 December 2020

Structure and function of an irreversible agonist-β(2) adrenoceptor complex

1 reference

12 December 2020

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

1 reference

12 December 2020

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

1 reference

12 December 2020

Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers

1 reference

12 December 2020

Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

1 reference

12 December 2020

G protein-coupled receptors show unusual patterns of intrinsic unfolding

1 reference

12 December 2020

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

1 reference

12 December 2020

Crystal structure of opsin in its G-protein-interacting conformation

1 reference

12 December 2020

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

1 reference

12 December 2020

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

12 December 2020

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

1 reference

12 December 2020

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

12 December 2020

Structure of an agonist-bound human A2A adenosine receptor

1 reference

12 December 2020

Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy

1 reference

12 December 2020

Progress in structure based drug design for G protein-coupled receptors

1 reference

12 December 2020

Two distinct conformations of helix 6 observed in antagonist-bound structures of a 1-adrenergic receptor

1 reference

12 December 2020

A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor

1 reference

12 December 2020

Critical features for biosynthesis, stability, and functionality of a G protein-coupled receptor uncovered by all-versus-all mutations

1 reference

12 December 2020

Potential use of G protein-coupled receptor-blocking monoclonal antibodies as therapeutic agents for cancers

1 reference

12 December 2020

Engineering G protein-coupled receptors to facilitate their structure determination.

1 reference

12 December 2020

Conserved activation pathways in G-protein-coupled receptors

1 reference

12 December 2020

Structure of the agonist-bound neurotensin receptor

1 reference

12 December 2020

The structural basis of agonist-induced activation in constitutively active rhodopsin

1 reference

12 December 2020

Location of the retinal chromophore in the activated state of rhodopsin*.

1 reference

12 December 2020

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

1 reference

12 December 2020

Structural diversity of G protein-coupled receptors and significance for drug discovery

1 reference

12 December 2020

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

12 December 2020

Conformational dynamics of single G protein-coupled receptors in solution

1 reference

12 December 2020

Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine

1 reference

12 December 2020

A G protein-coupled receptor at work: the rhodopsin model.

1 reference

12 December 2020

Pathway and mechanism of drug binding to G-protein-coupled receptors.

1 reference

12 December 2020

Structural and functional protein network analyses predict novel signaling functions for rhodopsin

1 reference

12 December 2020

Protein crystallography with a micrometre-sized synchrotron-radiation beam

1 reference

12 December 2020

Crystal structure of a lipid G protein-coupled receptor

1 reference

12 December 2020

Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor.

1 reference

12 December 2020

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

1 reference

12 December 2020

Structural insights into agonist-induced activation of G-protein-coupled receptors

1 reference

12 December 2020

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

1 reference

12 December 2020

Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

1 reference

12 December 2020

Site-directed mutagenesis of the putative human muscarinic M2 receptor binding site

1 reference

12 December 2020

Teaching old receptors new tricks: biasing seven-transmembrane receptors

1 reference

12 December 2020

Diversity and modularity of G protein-coupled receptor structures

1 reference

12 December 2020

Multiple ligand-specific conformations of the β2-adrenergic receptor

1 reference

12 December 2020

Molecular basis of ligand dissociation in β-adrenergic receptors

1 reference

12 December 2020

A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation

1 reference

12 December 2020

Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives

1 reference

12 December 2020

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

1 reference

12 December 2020

Structure of bovine rhodopsin in a trigonal crystal form.

1 reference

12 December 2020

Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions

1 reference

12 December 2020

Activation mechanism of the β2-adrenergic receptor

1 reference

12 December 2020

Crystallizing membrane proteins for structure determination: use of lipidic mesophases

1 reference

12 December 2020

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

1 reference

12 December 2020

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

1 reference

12 December 2020

The rules of disorder or why disorder rules

1 reference

12 December 2020

Crystal structure of squid rhodopsin

1 reference

12 December 2020

The minor binding pocket: a major player in 7TM receptor activation

1 reference

12 December 2020

Structure of the human κ-opioid receptor in complex with JDTic

1 reference

12 December 2020

Crystal structure of the β2 adrenergic receptor-Gs protein complex

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE11896

7 January 2021

inferred from DOI database lookup

Structure of the δ-opioid receptor bound to naltrindole

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE11896

7 January 2021

inferred from DOI database lookup

Discovery of 1,2,4-Triazine Derivatives as Adenosine A 2A Antagonists using Structure Based Drug Design

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE11896

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11896

1 reference

1 August 2017

1 reference