(Q35740222)

10 August 2017

title

Domain coupling in GPCRs: the engine for induced conformational changes (English)

1 reference

G protein-coupled receptor

10 August 2017

main subject

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author name string

Hamiyet Unal

series ordinal

1

1 reference

10 August 2017

Sadashiva S Karnik

series ordinal

2

1 reference

10 August 2017

language of work or name

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29 October 2011

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Trends in Pharmacological Sciences

10 August 2017

published in

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10 August 2017

volume

33

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10 August 2017

issue

2

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10 August 2017

page(s)

79-88

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

10 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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Importance of each residue within secretin for receptor binding and biological activity

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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New insights into the regulation of angiotensin receptors

12 July 2018

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Ligand binding and micro-switches in 7TM receptor structures

12 July 2018

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12 July 2018

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Thyrotropin and homologous glycoprotein hormone receptors: structural and functional aspects of extracellular signaling mechanisms

12 July 2018

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Alanine scanning mutagenesis of the second extracellular loop of type 1 corticotropin-releasing factor receptor revealed residues critical for peptide binding

12 July 2018

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

12 July 2018

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12 July 2018

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Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

12 July 2018

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Proteorhodopsins: an array of physiological roles?

12 July 2018

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How and why do GPCRs dimerize?

12 July 2018

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Structural diversity of G protein-coupled receptors and significance for drug discovery

12 July 2018

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The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction

12 July 2018

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

12 July 2018

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

12 July 2018

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Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors

12 July 2018

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Conformational complexity of G-protein-coupled receptors

12 July 2018

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12 July 2018

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A conformational contribution of the luteinizing hormone-receptor ectodomain to receptor activation

12 July 2018

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12 July 2018

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The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

12 July 2018

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Type 1 angiotensin receptor pharmacology: signaling beyond G proteins.

12 July 2018

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Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets

12 July 2018

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A viral conspiracy: hijacking the chemokine system through virally encoded pirated chemokine receptors

12 July 2018

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Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.

12 July 2018

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Ligand binding to the human MT2 melatonin receptor: the role of residues in transmembrane domains 3, 6, and 7.

12 July 2018

1 reference

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Transduction of receptor signals by beta-arrestins

12 July 2018

1 reference

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Dual role of interactions between membranous and soluble portions of helical membrane receptors for folding and signaling

12 July 2018

1 reference

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Essential role for the second extracellular loop in C5a receptor activation

12 July 2018

1 reference

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GPCR-interacting proteins (GIPs): nature and functions

12 July 2018

1 reference

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Roles of G-protein-coupled receptor dimerization

12 July 2018

1 reference

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The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice

12 July 2018

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Activation of G-protein-coupled receptors: a common molecular mechanism

12 July 2018

1 reference

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Retinal counterion switch in the photoactivation of the G protein-coupled receptor rhodopsin

12 July 2018

1 reference

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Agonist induction and conformational selection during activation of a G-protein-coupled receptor

12 July 2018

1 reference

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Seven-transmembrane receptors

12 July 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

12 July 2018

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Importance of the extracellular domain for prostaglandin EP(2) receptor function

12 July 2018

1 reference

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Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT1A) receptor

12 July 2018

1 reference

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GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor

12 July 2018

1 reference

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An inactivating mutation within the first extracellular loop of the thyrotropin receptor impedes normal posttranslational maturation of the extracellular domain.

25 September 2018

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The Secretin GPCRs descended from the family of Adhesion GPCRs.

25 September 2018

1 reference

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The repertoire of G-protein-coupled receptors in fully sequenced genomes

25 September 2018

1 reference

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Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II.

25 September 2018

1 reference

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The third extracellular loop of G-protein-coupled receptors: more than just a linker between two important transmembrane helices.

25 September 2018

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Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities

25 September 2018

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Considerations in the design and use of chimeric G protein-coupled receptors

25 September 2018

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12 December 2020

Analysis of structure-function from expression of G protein-coupled receptor fragments

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12 December 2020

RAMP-ing up class-B GPCR ECD structural coverage

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12 December 2020

Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide receptor chimeras reveal domains that determine specificity of vasoactive intestinal polypeptide binding and activation

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12 December 2020

Ligand binding pocket of the human somatostatin receptor 5: mutational analysis of the extracellular domains

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12 December 2020

Functionally discrete mimics of light-activated rhodopsin identified through expression of soluble cytoplasmic domains

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12 December 2020

The second extracellular loop: a damper for G protein-coupled receptors?

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12 December 2020

10.1016/J.TIPS.2011.09.007

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference