(Q27683539)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

protein-protein interaction

19 February 2020

main subject

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Shaomeng Wang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

8

Yali Dou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

Hacer Karatas

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Elizabeth C Townsend

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Fang Cao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Yong Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Liu Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Ming Lei

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

language of work or name

English

0 references

publication date

27 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Chemical Society

19 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

volume

135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

669-682

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis

19 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Chromatin modifications and their function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Regulation of MLL1 H3K4 methyltransferase activity by its core components

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

HOXA9 is required for survival in human MLL-rearranged acute leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Chromatin remodeling and cancer, Part I: Covalent histone modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Molecular recognition of histone H3 by the WD40 protein WDR5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Protein modules that manipulate histone tails for chromatin regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5180416

27 November 2018

Identifiers

DOI

10.1021/JA306028Q

2 references

Consolidated OpenCitations Corpus – April 2017

686616

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

release_ww4fvkq2yng5lehfbk6jpgyuyi

19 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ww4fvkq2yng5lehfbk6jpgyuyi

mapped directly with Wikidata item

24 November 2022

based on heuristic

686616

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23210835%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

23210835

2 references

Consolidated OpenCitations Corpus – April 2017

686616