(Q27688879)

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Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells

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Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells (English)

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Margarita Menéndez

object named as

Margarita Menéndez

6

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object named as

Dolores Solís

8

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object named as

Sabine André

5

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Hans-Joachim Gabius

object named as

Hans-Joachim Gabius

9

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Federico M Ruiz

object named as

Federico M Ruiz

1

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author name string

Barbara A Scholz

2

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Eliza Buzamet

3

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Jürgen Kopitz

4

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Antonio Romero

7

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language of work or name

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publication date

March 2014

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281

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5

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1446-64

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From lectin structure to functional glycomics: principles of the sugar code.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectins in acute and chronic inflammation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Lack of association between lymphotoxin-alpha, galectin-2 polymorphisms and coronary artery disease: a meta-analysis

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Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma

1 reference

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21 January 2018

Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study

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https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

A galectin-3 sequence polymorphism confers TRAIL sensitivity to human breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Apoptosis gene polymorphisms and risk of prostate cancer: a hospital-based study of German patients treated with brachytherapy

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-3 gene (LGALS3) +292C allele is a genetic predisposition factor for rheumatoid arthritis in Taiwan.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

The effect of galectin-3 genetic variants on the susceptibility and prognosis of gliomas in a Chinese population.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Unique chicken tandem-repeat-type galectin: implications of alternative splicing and a distinct expression profile compared to those of the three proto-type proteins

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8 functions as a matricellular modulator of cell adhesion

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Cyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8 induces apoptosis in the CD4(high)CD8(high) thymocyte subpopulation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8 provides costimulatory and proliferative signals to T lymphocytes.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8 tandem-repeat structure is essential for T-cell proliferation but not for co-stimulation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-1 and galectin-8 have redundant roles in promoting plasma cell formation

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Autoantibodies against galectin-8: their specificity, association with lymphopenia in systemic lupus erythematosus and detection in rheumatoid arthritis and acute inflammation.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Oligosaccharide specificity of galectins: a search by frontal affinity chromatography.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

The N-terminal carbohydrate recognition domain of galectin-8 recognizes specific glycosphingolipids with high affinity

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Carbohydrate specificity of chicken and human tandem-repeat-type galectins-8 in composition of cells.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Comparative study of the glycan specificities of cell-bound human tandem-repeat-type galectin-4, -8 and -9.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-8-N-domain Recognition Mechanism for Sialylated and Sulfated Glycans

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

N-domain of human adhesion/growth-regulatory galectin-9: preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Structural basis for recognition of autophagic receptor NDP52 by the sugar receptor galectin-8

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Sterical Hindrance Promotes Selectivity of the Autophagy Cargo Receptor NDP52 for the Danger Receptor Galectin-8 in Antibacterial Autophagy

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Detection of ligand- and solvent-induced shape alterations of cell-growth-regulatory human lectin galectin-1 in solution by small angle neutron and x-ray scattering.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Hydrodynamic properties of human adhesion/growth-regulatory galectins studied by fluorescence correlation spectroscopy

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Prototype chicken galectins revisited: characterization of a third protein with distinctive hydrodynamic behaviour and expression pattern in organs of adult animals

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Inference of macromolecular assemblies from crystalline state

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Pitfalls of predicting complex traits from SNPs

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Monomer/dimer equilibrium of the AB-type lectin from mistletoe enables combination of toxin/agglutinin activities in one protein: analysis of native and citraconylated proteins by ultracentrifugation/gel filtration and cell biological consequences o

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Single-site mutational engineering and following monoPEGylation of the human lectin galectin-2: effects on ligand binding, functional aspects, and clearance from serum.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Ganglioside GM1/galectin-dependent growth regulation in human neuroblastoma cells: special properties of bivalent galectin-4 and significance of linker length for ligand selection.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Human dectin-1 deficiency and mucocutaneous fungal infections

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

A novel function of Siglec-9 A391C polymorphism on T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Structural insights into the innate immune recognition specificities of L- and H-ficolins

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

The S128R polymorphism of E-selectin mediates neuraminidase-resistant tethering of myeloid cells under shear flow

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

T cells modulate glycans on CD43 and CD45 during development and activation, signal regulation, and survival

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

An A/G polymorphism of core 2 branching enzyme gene is associated with prostate cancer

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Matthews coefficient probabilities: Improved estimates for unit cell contents of proteins, DNA, and protein-nucleic acid complex crystals

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

Zinc Ions Induce the Unfolding and Self-Association of Boar Spermadhesin PSP-I, a Protein with a Single CUB Domain Architecture, and Promote Its Binding to Heparin†

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12716

21 January 2018

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