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Regulation of inflammatory and antiviral signaling by A20.
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PubMed
title
Regulation of inflammatory and antiviral signaling by A20.
(English)
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stated in
PubMed
main subject
inflammation
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author name string
Parvatiyar K
series ordinal
1
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PubMed
Harhaj EW
series ordinal
2
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stated in
PubMed
publication date
March 2011
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stated in
PubMed
published in
Microbes and Infection
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stated in
PubMed
volume
13
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PubMed
issue
3
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PubMed
page(s)
209-15
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PubMed
cites work
The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7
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PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4
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NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
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Direct activation of protein kinases by unanchored polyubiquitin chains
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ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways
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Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling
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TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL
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ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development
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Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation
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NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
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Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation
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T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20
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A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation
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Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
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Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
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Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
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A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter
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20 March 2017
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
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PubMed Central
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20 March 2017
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
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20 March 2017
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity
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PubMed Central
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A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells
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20 March 2017
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
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20 March 2017
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
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20 March 2017
Phosphorylation of CARMA1 plays a critical role in T Cell receptor-mediated NF-kappaB activation
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20 March 2017
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases
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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
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20 March 2017
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
1 reference
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PubMed Central
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20 March 2017
Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3
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PubMed Central
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20 March 2017
Modification of proteins by ubiquitin and ubiquitin-like proteins
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PubMed Central
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20 March 2017
The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031767
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20 March 2017
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
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PubMed Central
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20 March 2017
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031767
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20 March 2017
Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031767
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20 March 2017
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
1 reference
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PubMed Central
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20 March 2017
Signaling to NF-kappaB
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PubMed Central
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7 April 2017
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
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PubMed Central
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7 April 2017
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
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PubMed Central
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7 April 2017
The ubiquitin system
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7 April 2017
TAX1BP1 and A20 inhibit antiviral signaling by targeting TBK1-IKKi kinases
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29 September 2017
Targeting A20 decreases glioma stem cell survival and tumor growth
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29 September 2017
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031767
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29 September 2017
MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity
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29 September 2017
A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.
1 reference
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PubMed Central
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29 September 2017
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
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29 September 2017
Frequent inactivation of A20 in B-cell lymphomas
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29 September 2017
Ubiquitylation in innate and adaptive immunity.
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29 September 2017
The roles of TLRs, RLRs and NLRs in pathogen recognition
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29 September 2017
A20: central gatekeeper in inflammation and immunity
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PubMed Central
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29 September 2017
TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1
1 reference
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29 September 2017
TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme
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29 September 2017
Ubiquitin-mediated regulation of TNFR1 signaling
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29 September 2017
IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway
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PubMed Central
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29 September 2017
Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response
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29 September 2017
A20/TNFAIP3, a new estrogen-regulated gene that confers tamoxifen resistance in breast cancer cells.
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Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding
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Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.
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A20 is a negative regulator of IFN regulatory factor 3 signaling.
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29 September 2017
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation
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29 September 2017
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inferred from PubMed ID database lookup
Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling
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Identifiers
DOI
10.1016/J.MICINF.2010.11.003
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1827154
OpenCitations bibliographic resource ID
1827154
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1827154
PMC publication ID
3031767
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1827154
PubMed ID
21111841
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1827154
ResearchGate publication ID
49639718
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