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From "directed differentiation" to "neuronal induction": modeling neuropsychiatric disease
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title
From "directed differentiation" to "neuronal induction": modeling neuropsychiatric disease
(English)
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author name string
Ho SM
series ordinal
1
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Topol A
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2
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PubMed
Brennand KJ
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3
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PubMed
publication date
27 April 2015
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published in
Biomarker Insights
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Crossref
volume
10
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PubMed
issue
Suppl 1
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PubMed
page(s)
31-41
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PubMed
cites work
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Divergent reprogramming routes lead to alternative stem-cell states
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An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator
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Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients
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Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity
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Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders.
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Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons
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Modeling hippocampal neurogenesis using human pluripotent stem cells
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Valproate reverts zinc and potassium imbalance in schizophrenia-derived reprogrammed cells
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Deterministic direct reprogramming of somatic cells to pluripotency
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Glutamatergic postsynaptic density protein dysfunctions in synaptic plasticity and dendritic spines morphology: relevance to schizophrenia and other behavioral disorders pathophysiology, and implications for novel therapeutic approaches.
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29 September 2017
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29 September 2017
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29 September 2017
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
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29 September 2017
POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex
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Modeling human cortical development in vitro using induced pluripotent stem cells
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29 September 2017
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29 September 2017
Erosion of dosage compensation impacts human iPSC disease modeling
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29 September 2017
Disrupted-in-schizophrenia (DISC1) functions presynaptically at glutamatergic synapses
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29 September 2017
Direct conversion of fibroblasts into stably expandable neural stem cells
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29 September 2017
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
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29 September 2017
Interneuron dysfunction in psychiatric disorders
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Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
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29 September 2017
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
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29 September 2017
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
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Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia
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29 September 2017
Conversion of mouse and human fibroblasts into functional spinal motor neurons
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29 September 2017
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
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29 September 2017
MicroRNA-mediated conversion of human fibroblasts to neurons.
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29 September 2017
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
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29 September 2017
Direct conversion of human fibroblasts to dopaminergic neurons
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29 September 2017
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
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29 September 2017
Induced pluripotency: history, mechanisms, and applications
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29 September 2017
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits
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29 September 2017
Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome
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29 September 2017
ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms
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29 September 2017
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
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29 September 2017
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29 September 2017
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29 September 2017
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
29 September 2017
Distinct cortical migrations from the medial and lateral ganglionic eminences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
29 September 2017
Proteome adaptation in cell reprogramming proceeds via distinct transcriptional networks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Small RNA changes en route to distinct cellular states of induced pluripotency.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Synaptic dysregulation in a human iPS cell model of mental disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Human iPSC-based modeling of late-onset disease via progerin-induced aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Stimulation of P2 receptors in the ventral tegmental area enhances dopaminergic mechanisms in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
2 June 2018
Derivation of novel human ground state naive pluripotent stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Dopaminergic differentiation of human pluripotent cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4444490
retrieved
27 November 2018
Different flavors of pluripotency, molecular mechanisms, and practical implications
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26045654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4137/BMI.S20066
1 reference
stated in
PubMed
PMCID
4444490
1 reference
stated in
PubMed
PubMed ID
26045654
1 reference
stated in
PubMed
ResearchGate publication ID
277778395
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