(Q34503763)

2 August 2017

title

Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons (English)

1 reference

amyotrophic lateral sclerosis

2 August 2017

main subject

1 reference

Hong Chen

1

1 reference

2 August 2017

Kun Qian

2

1 reference

2 August 2017

Zhongwei Du

3

1 reference

2 August 2017

Jingyuan Cao

4

1 reference

2 August 2017

Andrew Petersen

5

1 reference

2 August 2017

Huisheng Liu

6

1 reference

2 August 2017

Lisle W Blackbourn

7

1 reference

2 August 2017

CindyTzu-Ling Huang

8

1 reference

2 August 2017

Anthony Errigo

9

1 reference

2 August 2017

Yingnan Yin

10

1 reference

2 August 2017

Jianfeng Lu

11

1 reference

2 August 2017

Melvin Ayala

12

1 reference

2 August 2017

Su-Chun Zhang

13

1 reference

2 August 2017

language of work or name

English

0 references

publication date

3 April 2014

1 reference

2 August 2017

1 reference

2 August 2017

volume

14

1 reference

2 August 2017

issue

6

1 reference

2 August 2017

page(s)

796-809

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4230530/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Specification of transplantable astroglial subtypes from human pluripotent stem cells

7 July 2018

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D90A-SOD1 mutation in ALS: The first report of heterozygous Italian patients and unusual findings

7 July 2018

1 reference

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Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

7 July 2018

1 reference

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Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease

7 July 2018

1 reference

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

7 July 2018

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Age and founder effect of SOD1 A4V mutation causing ALS

7 July 2018

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Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

7 July 2018

1 reference

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Human embryonic stem cell-derived neural precursors develop into neurons and integrate into the host brain

7 July 2018

1 reference

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Transgenic mouse models of amyotrophic lateral sclerosis

7 July 2018

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Mutant copper-zinc superoxide dismutase binds to and destabilizes human low molecular weight neurofilament mRNA.

7 July 2018

1 reference

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Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice.

7 July 2018

1 reference

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Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

7 July 2018

1 reference

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Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant

7 July 2018

1 reference

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Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230530

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

7 July 2018

1 reference

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

7 July 2018

1 reference

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

7 July 2018

1 reference

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

7 July 2018

1 reference

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Microheterogeneity ("neurotypy") of neurofilament proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230530

Proximal axonal enlargement in motor neuron disease.

7 July 2018

1 reference

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Novel monoclonal antibodies provide evidence for the in situ existence of a nonphosphorylated form of the largest neurofilament subunit.

7 July 2018

1 reference

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The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons

7 July 2018

1 reference

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A simple and efficient system for regulating gene expression in human pluripotent stem cells and derivatives

7 July 2018

1 reference

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Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

27 October 2018

1 reference

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230530

Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230530

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

27 October 2018

1 reference

12 December 2020

Neurofilament light and polyadenylated mRNA levels are decreased in amyotrophic lateral sclerosis motor neurons

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis

1 reference

12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

12 December 2020

Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS

1 reference

12 December 2020

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

1 reference

12 December 2020

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

12 December 2020

10.1016/J.STEM.2014.02.004

Identifiers

DOI

1 reference

2 August 2017

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2 August 2017

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