(Q30537986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

0 references

1

1 reference

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23 February 2020

Dale Michael Ando

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Rick Siller

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Agnes Lumi Nishimura

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Christopher Shaw

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

14

Ian Wilmut

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Bilada Bilican

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Sami J Barmada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Chen Zhao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Karen Burr

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ghazal Haghi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

David Story

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Monica A Carrasco

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Hemali P Phatnani

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Carole Shum

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Steven Finkbeiner

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Siddharthan Chandran

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Tom Maniatis

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

11 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

110

1 reference

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23 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

4697-4702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

23 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3607024/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Drug screening for ALS using patient-specific induced pluripotent stem cells

20 June 2018

1 reference

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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Specification of transplantable astroglial subtypes from human pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

TDP-43 regulates its mRNA levels through a negative feedback loop

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Suppression of the intrinsic apoptosis pathway by synaptic activity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

20 June 2018

1 reference

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A new subtype of frontotemporal lobar degeneration with FUS pathology

20 June 2018

1 reference

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Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

20 June 2018

1 reference

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Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

20 June 2018

1 reference

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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

20 June 2018

1 reference

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Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.

20 June 2018

1 reference

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis

20 June 2018

1 reference

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Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

20 June 2018

1 reference

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Automated microscope system for determining factors that predict neuronal fate.

20 June 2018

1 reference

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BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Control of synapse number by glia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Neuronal vs. glial fate of embryonic stem cell-derived neural progenitors (ES-NPs) is determined by FGF2/EGF during proliferation.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1300398110

Committed neuronal precursors confer astrocytic potential on residual neural precursor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1300398110

The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1300398110

Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1300398110

Temporal and spatial analysis of astrocyte calcium waves.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Epidermal Growth Factor Receptors Control Competence to Interpret Leukemia Inhibitory Factor as an Astrocyte Inducer in Developing Cortex

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3607024

Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis

26 November 2018

1 reference

12 December 2020

ATP released from astrocytes mediates glial calcium waves

1 reference

12 December 2020

Purification and characterization of astrocyte precursor cells in the developing rat optic nerve

1 reference

12 December 2020

Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1300398110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

23401527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23401527%20AND%20SRC:MED&resulttype=core&format=json