(Q27703282)

4

object named as

F Ulrich Hartl

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author name string

Tobias Neudegger

1

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Jacob Verghese

2

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Andreas Bracher

Nature Structural & Molecular Biology

5

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publication date

February 2016

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published in

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volume

23

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issue

2

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page(s)

140-6

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cites work

Adapting proteostasis for disease intervention

1 reference

Regulation of HSF1 function in the heat stress response: implications in aging and disease

21 April 2017

1 reference

Crystal structure of the DNA binding domain of the heat shock transcription factor

21 April 2017

1 reference

Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor

21 April 2017

1 reference

A new use for the 'wing' of the 'winged' helix-turn-helix motif in the HSF-DNA cocrystal

21 April 2017

1 reference

Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1

21 April 2017

1 reference

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress

21 April 2017

1 reference

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

21 April 2017

1 reference

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

21 April 2017

1 reference

Activation of the DNA-binding ability of human heat shock transcription factor 1 may involve the transition from an intramolecular to an intermolecular triple-stranded coiled-coil structure

21 April 2017

1 reference

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression

21 April 2017

1 reference

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

21 April 2017

1 reference

Molecular chaperones as HSF1-specific transcriptional repressors

21 April 2017

1 reference

Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1

21 April 2017

1 reference

The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status

21 April 2017

1 reference

Isolation of the gene encoding the S. cerevisiae heat shock transcription factor

21 April 2017

1 reference

The Skn7 response regulator controls gene expression in the oxidative stress response of the budding yeast Saccharomyces cerevisiae

21 April 2017

1 reference

The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p

21 April 2017

1 reference

Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

21 April 2017

1 reference

Protein homeostasis as a therapeutic target for diseases of protein conformation

21 April 2017

1 reference

21 April 2017

1 reference

Scaling and assessment of data quality

21 April 2017

1 reference

The CCP4 suite: programs for protein crystallography

21 April 2017

1 reference

Experimental phasing with SHELXC/D/E: combining chain tracing with density modification

21 April 2017

1 reference

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

21 April 2017

1 reference

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

21 April 2017

1 reference

Comparative protein modelling by satisfaction of spatial restraints

21 April 2017

1 reference

ModLoop: automated modeling of loops in protein structures

21 April 2017

1 reference

UCSF Chimera--a visualization system for exploratory research and analysis

21 April 2017

1 reference

ESPript: analysis of multiple sequence alignments in PostScript

21 April 2017

1 reference

How good are my data and what is the resolution?

21 April 2017

1 reference

Modeling of loops in protein structures

21 April 2017

1 reference

Molecular chaperone functions in protein folding and proteostasis

21 April 2017

1 reference

Heat shock factors: integrators of cell stress, development and lifespan.

21 January 2018

1 reference

Protein folding in the cytoplasm and the heat shock response

21 January 2018

1 reference

The heat shock response: systems biology of proteotoxic stress in aging and disease

21 January 2018

1 reference

A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene.

21 January 2018

1 reference

Key features of heat shock regulatory elements

21 January 2018

1 reference

Germline transformation used to define key features of heat-shock response elements.

21 January 2018

1 reference

The carboxy-terminal domain of heat-shock factor 1 is largely unfolded but can be induced to collapse into a compact, partially structured state.

21 January 2018

1 reference

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

21 January 2018

1 reference

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

21 January 2018

1 reference

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

21 January 2018

1 reference

Regulation of heat shock factor trimer formation: role of a conserved leucine zipper

21 January 2018

1 reference

Genetic selection for constitutively trimerized human HSF1 mutants identifies a role for coiled-coil motifs in DNA binding

21 January 2018

1 reference

A direct regulatory interaction between chaperonin TRiC and stress-responsive transcription factor HSF1.

21 January 2018

1 reference

Dynamic remodeling of transcription complexes by molecular chaperones

21 January 2018

1 reference

Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation

21 January 2018

1 reference

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

21 January 2018

1 reference

Highly conserved repetitive DNA sequences are present at human centromeres

21 January 2018

1 reference

Human chromosomes 9, 12, and 15 contain the nucleation sites of stress-induced nuclear bodies

21 January 2018

1 reference

In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress.

21 January 2018

1 reference

Stress-induced transcription of satellite III repeats.

21 January 2018

1 reference

A key role for stress-induced satellite III transcripts in the relocalization of splicing factors into nuclear stress granules

21 January 2018

1 reference

Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress

21 January 2018

1 reference

Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity

21 January 2018

1 reference

Cooperative binding of Drosophila heat shock factor to arrays of a conserved 5 bp unit.

21 January 2018

1 reference

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation.

21 January 2018

1 reference

Fungal Skn7 stress responses and their relationship to virulence

21 January 2018

1 reference

The yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p

21 January 2018

1 reference

Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.

21 January 2018

1 reference

Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy

21 January 2018

1 reference

A single amino acid can determine the DNA binding specificity of homeodomain proteins.

21 January 2018

1 reference

An efficient system for high-level expression and easy purification of authentic recombinant proteins

21 January 2018

1 reference

Genomic heat shock element sequences drive cooperative human heat shock factor 1 DNA binding and selectivity

21 January 2018

1 reference

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

21 January 2018

1 reference

Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps

21 January 2018

1 reference

Heat shock transcription factors: structure and regulation

21 January 2018

1 reference

In vitro activation of purified human heat shock factor by heat

31 March 2020

1 reference

Trimerization of the heat shock transcription factor by a triple-stranded alpha-helical coiled-coil

31 March 2020

1 reference

Engrailed (Gln50→Lys) homeodomain–DNA complex at 1.9 Å resolution: structural basis for enhanced affinity and altered specificity

31 March 2020

1 reference

On the treatment of negative intensity observations

31 March 2020

1 reference

Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity

31 March 2020

1 reference

12 December 2020

Yeast heat shock transcription factor contains a flexible linker between the DNA-binding and trimerization domains. Implications for DNA binding by trimeric proteins.

1 reference

12 December 2020

Human heat shock factor 1 is predominantly a nuclear protein before and after heat stress

1 reference

12 December 2020

Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.3149

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4277242

Dimensions Publication ID

1019303632

0 references

OpenCitations bibliographic resource ID

4277242

1 reference