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On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
scientific article
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instance of
scholarly article
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
title
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
(English)
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
main subject
kidney cancer
1 reference
based on heuristic
inferred from title
author
William G. Kaelin
series ordinal
12
object named as
William G Kaelin
1 reference
stated in
Q5412157
retrieved
25 September 2017
PMCID
5499381
Sabina Signoretti
series ordinal
8
object named as
Sabina Signoretti
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
author name string
Hyejin Cho
series ordinal
1
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Xinlin Du
series ordinal
2
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
James P Rizzi
series ordinal
3
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Ella Liberzon
series ordinal
4
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Abhishek A Chakraborty
series ordinal
5
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Wenhua Gao
series ordinal
6
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Ingrid Carvo
series ordinal
7
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
John A Josey
series ordinal
10
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Eli M Wallace
series ordinal
11
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Richard K Bruick
series ordinal
9
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
language of work or name
English
0 references
publication date
5 September 2016
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
number of pages
5
1 reference
based on heuristic
inferred from page(s)
published in
Nature
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
volume
539
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
page(s)
107-111
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
issue
7627
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
describes a project that uses
ImageJ
1 reference
stated in
Q5412157
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5499381/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Targeting renal cell carcinoma with a HIF-2 antagonist.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Artificial ligand binding within the HIF2 PAS-B domain of the HIF2 transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
29 September 2017
Tumour suppression by the human von Hippel-Lindau gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499381
retrieved
2 June 2018
A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNATURE19795
retrieved
21 January 2018
Identifiers
DOI
10.1038/NATURE19795
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Dimensions Publication ID
1012677868
0 references
PMCID
5499381
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
PubMed ID
27595393
1 reference
stated in
Q5412157
PMCID
5499381
retrieved
25 September 2017
Springer Nature article ID
10.1038/nature19795
0 references
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