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MEK1 mutations confer resistance to MEK and B-RAF inhibition
scientific article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
19915144
retrieved
13 November 2016
title
MEK1 mutations confer resistance to MEK and B-RAF inhibition
(English)
1 reference
stated in
PubMed
PubMed ID
19915144
retrieved
13 November 2016
author
Reinhard Dummer
series ordinal
15
0 references
Levi A Garraway
series ordinal
16
object named as
Levi A Garraway
0 references
Nathanael Gray
series ordinal
13
object named as
Nathanael S Gray
0 references
author name string
Caroline M Emery
series ordinal
1
0 references
Krishna G Vijayendran
series ordinal
2
0 references
Marie C Zipser
series ordinal
3
0 references
Allison M Sawyer
series ordinal
4
0 references
Lili Niu
series ordinal
5
0 references
Jessica J Kim
series ordinal
6
0 references
Charles Hatton
series ordinal
7
0 references
Rajiv Chopra
series ordinal
8
0 references
Patrick A Oberholzer
series ordinal
9
0 references
Maria B Karpova
series ordinal
10
0 references
Laura E MacConaill
series ordinal
11
0 references
Jianming Zhang
series ordinal
12
0 references
William R Sellers
series ordinal
14
0 references
language of work or name
English
0 references
publication date
1 December 2009
0 references
published in
Proceedings of the National Academy of Sciences of the United States of America
0 references
volume
106
0 references
page(s)
20411-6
0 references
issue
48
0 references
cites work
Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Accurate whole human genome sequencing using reversible terminator chemistry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Mutations of the BRAF gene in human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
20 March 2017
BRAF mutation predicts sensitivity to MEK inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
7 April 2017
Cancer. Addiction to oncogenes--the Achilles heal of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
7 April 2017
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
7 April 2017
(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype-phenotype correlations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Modeling genomic diversity and tumor dependency in malignant melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Mutation analysis of BRAF, MEK1 and MEK2 in 15 ovarian cancer cell lines: implications for therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Cardio-facio-cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype-phenotype relationships and overlap with Costello syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in precl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Cell signaling and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Identification of a novel mitogen-activated protein kinase kinase activation domain recognized by the inhibitor PD 184352.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777185
retrieved
29 September 2017
Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0905833106
retrieved
21 January 2018
Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0905833106
retrieved
21 January 2018
Biochemical characterization of novel germline BRAF and MEK mutations in cardio-facio-cutaneous syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0905833106
retrieved
21 January 2018
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0905833106
retrieved
21 January 2018
High-throughput oncogene mutation profiling in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0905833106
retrieved
21 January 2018
Identifiers
DOI
10.1073/PNAS.0905833106
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1503785
ADS bibcode
2009PNAS..10620411E
0 references
Fatcat ID
release_e4hvjcspdnaulldln4ppcg22pm
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/e4hvjcspdnaulldln4ppcg22pm
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
1503785
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1503785
PMCID
2777185
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1503785
PubMed ID
19915144
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1503785
ResearchGate publication ID
38091087
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