(Q27851680)

13 November 2016

title

Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic study of 277 patients (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

9

A Tefferi

0 references

author name string

M M Patnaik

1

0 references

C A Hanson

2

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J M Hodnefield

3

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T L Lasho

4

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C M Finke

5

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R A Knudson

6

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R P Ketterling

7

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A Pardanani

An integrated genomic analysis of human glioblastoma multiforme

8

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publication date

January 2012

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published in

Leukemia

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volume

26

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issue

1

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page(s)

101-5

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cites work

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

Recurring mutations found by sequencing an acute myeloid leukemia genome

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

The prognostic significance of IDH2 mutations in AML depends on the location of the mutation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

21 April 2017

1 reference

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/LEU.2011.298

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group

21 April 2017

1 reference

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Mutations of IDH1 and IDH2 genes in early and accelerated phases of myelodysplastic syndromes and MDS/myeloproliferative neoplasms

21 January 2018

1 reference

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IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis.

21 January 2018

1 reference

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Recurrent IDH mutations in high-risk myelodysplastic syndrome or acute myeloid leukemia with isolated del(5q).

21 January 2018

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IDH mutations and trisomy 8 in myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

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The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

21 January 2018

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MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients

21 January 2018

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Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates

21 January 2018

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JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

Isolated del(5q) in myeloid malignancies: clinicopathologic and molecular features in 143 consecutive patients.

21 January 2018

1 reference

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IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

The prognostic impact and stability of Isocitrate dehydrogenase 2 mutation in adult patients with acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

inferred from DOI database lookup

7 January 2021

based on heuristic

IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298

inferred from DOI database lookup

7 January 2021

based on heuristic

Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.298