Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q27851720)
Watch
English
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
22328973
retrieved
13 November 2016
title
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
(English)
1 reference
stated in
PubMed
PubMed ID
22328973
retrieved
13 November 2016
main subject
lung cancer
1 reference
based on heuristic
inferred from title
author
Wendy Winckler
series ordinal
48
0 references
Heidi Greulich
series ordinal
49
0 references
Kwok Kin Wong
series ordinal
54
object named as
Kwok-Kin Wong
0 references
Lear Brace
object named as
Lear E Brace
series ordinal
7
0 references
Joachim H Clement
object named as
Joachim H Clement
series ordinal
35
0 references
Martin Peifer
object named as
Martin Peifer
series ordinal
14
0 references
Amit Dutt
object named as
Amit Dutt
series ordinal
5
0 references
Daniel Rauh
object named as
Daniel Rauh
series ordinal
52
0 references
Wim Timens
object named as
Wim Timens
series ordinal
37
0 references
Ming-Sound Tsao
object named as
Ming Sound Tsao
series ordinal
42
0 references
Åslaug Helland
series ordinal
33
object named as
Aslaug Helland
0 references
Odd Terje Brustugun
series ordinal
32
object named as
Odd Terje Brustugun
0 references
Matthew Meyerson
series ordinal
57
object named as
Matthew Meyerson
0 references
Elisabeth Brambilla
series ordinal
29
object named as
Elisabeth Brambilla
0 references
Pasi A Jänne
series ordinal
46
object named as
Pasi A Janne
0 references
Nathanael Gray
series ordinal
53
object named as
Nathanael S Gray
0 references
Charles Hatton
object named as
Charles Hatton
series ordinal
44
1 reference
stated in
ORCID Public Data File 2021
Helga Salvesen
series ordinal
18
object named as
Helga B Salvesen
0 references
Holger Moch
series ordinal
23
object named as
Holger Moch
0 references
Harry J M Groen
series ordinal
36
object named as
Harry Groen
0 references
author name string
Peter S Hammerman
series ordinal
1
0 references
Martin L Sos
series ordinal
2
0 references
Alex H Ramos
series ordinal
3
0 references
Chunxiao Xu
series ordinal
4
0 references
Wenjun Zhou
series ordinal
6
0 references
Brittany A Woods
series ordinal
8
0 references
Wenchu Lin
series ordinal
9
0 references
Jianming Zhang
series ordinal
10
0 references
Xianming Deng
series ordinal
11
0 references
Sang Min Lim
series ordinal
12
0 references
Stefanie Heynck
series ordinal
13
0 references
Jeffrey R Simard
series ordinal
15
0 references
Michael S Lawrence
series ordinal
16
0 references
Robert C Onofrio
series ordinal
17
0 references
Danila Seidel
series ordinal
19
0 references
Thomas Zander
series ordinal
20
0 references
Johannes M Heuckmann
series ordinal
21
0 references
Alex Soltermann
series ordinal
22
0 references
Mirjam Koker
series ordinal
24
0 references
Frauke Leenders
series ordinal
25
0 references
Franziska Gabler
series ordinal
26
0 references
Silvia Querings
series ordinal
27
0 references
Sascha Ansén
series ordinal
28
0 references
Christian Brambilla
series ordinal
30
0 references
Philippe Lorimier
series ordinal
31
0 references
Iver Petersen
series ordinal
34
0 references
Hannie Sietsma
series ordinal
38
0 references
Erich Stoelben
series ordinal
39
0 references
Jürgen Wolf
series ordinal
40
0 references
David G Beer
series ordinal
41
0 references
Megan Hanna
series ordinal
43
0 references
Michael J Eck
series ordinal
45
0 references
Bruce E Johnson
series ordinal
47
0 references
Adam J Bass
series ordinal
50
0 references
Jeonghee Cho
series ordinal
51
0 references
Eric B Haura
series ordinal
55
0 references
Roman K Thomas
series ordinal
56
0 references
language of work or name
English
0 references
publication date
June 2011
0 references
published in
Cancer Discovery
1 reference
stated in
PubMed
volume
1
0 references
page(s)
78-89
0 references
issue
1
0 references
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3274752/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
The biology and treatment of EML4-ALK non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
High-resolution genomic profiles of human lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
The discoidin domain receptor tyrosine kinases are activated by collagen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Extended kinase profile and properties of the protein kinase inhibitor nilotinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
A quantitative analysis of kinase inhibitor selectivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
20 March 2017
The landscape of somatic copy-number alteration across human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
7 April 2017
Diverse somatic mutation patterns and pathway alterations in human cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
7 April 2017
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
7 April 2017
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
7 April 2017
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
7 April 2017
Phase II study of dasatinib in patients with advanced non-small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Targeted cancer therapies in the twenty-first century: lessons from imatinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
A chemical and phosphoproteomic characterization of dasatinib action in lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Dasatinib in solid tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Histologic considerations for individualized systemic therapy approaches for the management of non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Quality indicators in cancer care: development and implementation for improved health outcomes in non-small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Amplification of chromosomal segment 4q12 in non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Imatinib and beyond--exploring the full potential of targeted therapy for CML.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Mutations in DDR2 gene cause SMED with short limbs and abnormal calcifications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Highly parallel identification of essential genes in cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Somatic mutations of the protein kinase gene family in human lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Discoidin domain receptors: structural relations and functional implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
29 September 2017
Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: synthesis and structure-activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
27 November 2018
Molecular analysis of collagen binding by the human discoidin domain receptors, DDR1 and DDR2. Identification of collagen binding sites in DDR2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3274752
retrieved
27 November 2018
Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22328973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/2159-8274.CD-11-0005
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2107688
OpenCitations bibliographic resource ID
2107688
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2107688
PMCID
3274752
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2107688
PubMed ID
22328973
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2107688
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit