Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q27853011)
Watch
English
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib
scientific article
Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
24869598
retrieved
13 November 2016
title
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib
(English)
1 reference
stated in
PubMed
PubMed ID
24869598
retrieved
13 November 2016
main subject
ibrutinib
1 reference
based on heuristic
inferred from title
author
Jacqueline Barrientos
series ordinal
19
object named as
Jacqueline C Barrientos
0 references
Stephan Stilgenbauer
series ordinal
21
object named as
Stephan Stilgenbauer
0 references
John C. Byrd
series ordinal
25
object named as
John C Byrd
0 references
Peter Lichter
series ordinal
20
object named as
Peter Lichter
0 references
Amy S Ruppert
series ordinal
6
object named as
Amy S Ruppert
0 references
Danelle F James
series ordinal
18
object named as
Danelle F James
0 references
Jennifer A Woyach
series ordinal
1
object named as
Jennifer A Woyach
0 references
Kristie A Blum
series ordinal
15
object named as
Kristie A Blum
0 references
Gerard Lozanski
series ordinal
17
object named as
Gerard Lozanski
0 references
Samantha M Jaglowski
series ordinal
14
object named as
Samantha M Jaglowski
0 references
Arletta Lozanski
series ordinal
16
object named as
Arletta Lozanski
0 references
author name string
Richard R Furman
series ordinal
2
0 references
Ta-Ming Liu
series ordinal
3
0 references
Hatice Gulcin Ozer
series ordinal
4
0 references
Marc Zapatka
series ordinal
5
0 references
Ling Xue
series ordinal
7
0 references
Daniel Hsieh-Hsin Li
series ordinal
8
0 references
Susanne M Steggerda
series ordinal
9
0 references
Matthias Versele
series ordinal
10
0 references
Sandeep S Dave
series ordinal
11
0 references
Jenny Zhang
series ordinal
12
0 references
Ayse Selen Yilmaz
series ordinal
13
0 references
Joseph J Buggy
series ordinal
22
0 references
Betty Y Chang
series ordinal
23
0 references
Amy J Johnson
series ordinal
24
0 references
language of work or name
English
0 references
publication date
12 June 2014
0 references
published in
The New England Journal of Medicine
0 references
volume
370
0 references
issue
24
0 references
page(s)
2286-94
0 references
cites work
Acquired Resistance to Crizotinib from a Mutation in CD74 – ROS1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
Fast and accurate short read alignment with Burrows-Wheeler transform
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
20 March 2017
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
7 April 2017
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
7 April 2017
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
7 April 2017
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
7 April 2017
Ibrutinib resistance in chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Mechanisms of primary and secondary resistance to imatinib in chronic myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
BTKbase: the mutation database for X-linked agammaglobulinemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
B cell antigen receptor signaling 101.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
29 September 2017
Survival response to B-cell receptor ligation is restricted to progressive chronic lymphocytic leukemia cells irrespective of Zap70 expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
27 November 2018
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4144824
retrieved
27 November 2018
Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24869598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Survival of leukemic B cells promoted by engagement of the antigen receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24869598
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1056/NEJMOA1400029
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1116042
OpenCitations bibliographic resource ID
1116042
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1116042
PMCID
4144824
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1116042
PubMed ID
24869598
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1116042
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit