(Q27853170)

13 November 2016

title

Integrative clinical genomics of advanced prostate cancer (English)

1 reference

PubMed

PubMed publication ID

13 November 2016

0 references

1 reference

39

0 references

Olivier Elemento

62

Olivier Elemento

0 references

Susana Miranda

Susana Miranda

50

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Heidi Dvinge

Heidi Dvinge

47

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Jeremy C Durack

Jeremy C Durack

30

0 references

Robert K. Bradley

Robert K Bradley

13

0 references

Dana E Rathkopf

Dana E Rathkopf

27

0 references

Francesca Demichelis

Francesca Demichelis

55

0 references

Michael J. Morris

Michael J Morris

28

0 references

Gerhardt Attard

Gerhardt Attard

10

0 references

David C. Smith

David C Smith

22

0 references

Kathleen A. Cooney

Kathleen A Cooney

21

0 references

Mark Rubin

Mark A Rubin

69

0 references

Philip W. Kantoff

Philip Kantoff

67

0 references

Massimo Loda

34

Massimo Loda

0 references

Nikolaus Schultz

4

Nikolaus Schultz

0 references

Mary-Ellen Taplin

8

Mary-Ellen Taplin

0 references

Levi A Garraway

71

Levi A Garraway

0 references

Kenneth J. Pienta

66

Kenneth J Pienta

0 references

Arul Chinnaiyan

73

Arul M Chinnaiyan

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Johann de Bono

68

Johann S de Bono

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Andrea Sboner

63

Andrea Sboner

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Himisha Beltran

11

Himisha Beltran

0 references

Juan Miguel Mosquera

6

Juan-Miguel Mosquera

0 references

Scott A Tomlins

20

Scott A Tomlins

0 references

Xuhong Cao

15

Xuhong Cao

0 references

Victor Reuter

31

Victor E Reuter

0 references

Martin R. Delany

1

Dan Robinson

0 references

Eliezer Van Allen

2

Eliezer M Van Allen

0 references

Robert J Lonigro

5

Robert J Lonigro

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Donald Bruce Montgomery

7

Bruce Montgomery

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Wassim Abida

12

Wassim Abida

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Lakshmi P Kunju

17

Lakshmi P Kunju

0 references

Felix Y Feng

19

Felix Y Feng

0 references

Jianjiong Gao

33

Jianjiong Gao

0 references

Lawrence D True

45

Lawrence D True

0 references

Zafeiris Zafeiriou

51

Zafeiris Zafeiriou

0 references

David M Nanus

58

David M Nanus

0 references

Scott T Tagawa

59

Scott T Tagawa

0 references

Jake Vinson

14

Jake Vinson

0 references

Pankaj Vats

16

Pankaj Vats

0 references

Maha Hussain

18

Maha Hussain

0 references

Christine Brennan

23

Christine Brennan

0 references

Stephen B Solomon

29

Stephen B Solomon

0 references

Anuradha Gopalan

32

Anuradha Gopalan

0 references

Rosina T Lis

35

Rosina T Lis

0 references

Michaela Bowden

36

Michaela Bowden

0 references

Stephen P Balk

37

Stephen P Balk

0 references

Glenn Gaviola

38

Glenn Gaviola

0 references

Manaswi Gupta

40

Manaswi Gupta

0 references

Elahe A Mostaghel

42

Elahe A Mostaghel

0 references

Heather H Cheng

43

Heather H Cheng

0 references

Hyojeong Mulcahy

44

Hyojeong Mulcahy

0 references

Stephen R Plymate

46

Stephen R Plymate

0 references

Roberta Ferraldeschi

48

Roberta Ferraldeschi

0 references

Penny Flohr

49

Penny Flohr

0 references

Nina Tunariu

52

Nina Tunariu

0 references

Joaquin Mateo

53

Joaquin Mateo

0 references

Raquel Perez-Lopez

54

Raquel Perez-Lopez

0 references

Marc Schiffman

57

Marc Schiffman

0 references

Alexandros Sigaras

60

Alexandros Sigaras

0 references

Kenneth Eng

61

Kenneth W Eng

0 references

Elisabeth I Heath

64

Elisabeth I Heath

0 references

Howard I Scher

65

Howard I Scher

0 references

Peter S Nelson

70

Peter S Nelson

0 references

author name string

Yi-Mi Wu

3

0 references

Colin C Pritchard

9

0 references

Javed Siddiqui

24

0 references

Rohit Mehra

25

0 references

Yu Chen

26

0 references

Evan Y Yu

41

0 references

Brian D Robinson

56

0 references

Charles L Sawyers

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

72

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language of work or name

English

0 references

publication date

21 May 2015

0 references

published in

Cell

0 references

volume

161

0 references

issue

5

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page(s)

1215-28

0 references

cites work

1 reference

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20 March 2017

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20 March 2017

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20 March 2017

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Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer

20 March 2017

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Abiraterone in metastatic prostate cancer without previous chemotherapy

20 March 2017

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

20 March 2017

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

20 March 2017

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TopHat-Fusion: an algorithm for discovery of novel fusion transcripts

20 March 2017

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The genomic complexity of primary human prostate cancer

20 March 2017

1 reference

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The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

20 March 2017

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

A census of human cancer genes

20 March 2017

1 reference

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Discovery and saturation analysis of cancer genes across 21 tumour types

20 March 2017

1 reference

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

20 March 2017

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

20 March 2017

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Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Integrative genomics viewer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Increased survival with enzalutamide in prostate cancer after chemotherapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

The mutational landscape of lethal castration-resistant prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Abiraterone and increased survival in metastatic prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Integrative genomic profiling of human prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Circular binary segmentation for the analysis of array-based DNA copy number data

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

The evolutionary history of lethal metastatic prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

RNF43 is frequently mutated in colorectal and endometrial cancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Tumor clone dynamics in lethal prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Organoid cultures derived from patients with advanced prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Copy number alteration burden predicts prostate cancer relapse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Enzalutamide in metastatic prostate cancer before chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

PLZF mediates the PTEN/AKT/FOXO3a signaling in suppression of prostate tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Targeting cell cycle and hormone receptor pathways in cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Punctuated evolution of prostate cancer genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Recurrent R-spondin fusions in colon cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Characterization of KRAS rearrangements in metastatic prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Personalized oncology through integrative high-throughput sequencing: a pilot study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Detection of somatic copy number alterations in cancer using targeted exome capture sequencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

PTEN-deficient cancers depend on PIK3CB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Proposed morphologic classification of prostate cancer with neuroendocrine differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Characterization of bone metastases from rapid autopsies of prostate cancer patients

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Integrated genomic characterization of adrenocortical carcinoma.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Beta-catenin mutations in human prostate cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484602

Commentary on "The evolutionary history of lethal metastatic prostate cancer." Gundem G, Van Loo P, Kremeyer B, Alexandrov LB, Tubio JM, Papaemmanuil E, Brewer DS, Kallio HM, Högnäs G, Annala M, Kivinummi K, Goody V, Latimer C, O'Meara S, Dawson KJ,

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26000489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Commentary on "Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer." Hong MK, Macintyre G, Wedge DC, Van Loo P, Patel K, Lunke S, Alexandrov LB, Sloggett C, Cmero M, Marass F, Tsui D, Mangiola S, Lonie A, Naeem H, S

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26000489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2015.05.001

1 reference

1 reference

1 reference

PubMed publication ID

26000489

1 reference