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Blm10 facilitates nuclear import of proteasome core particles
scientific article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23982732
retrieved
1 December 2016
title
Blm10 facilitates nuclear import of proteasome core particles
(English)
1 reference
stated in
PubMed
PubMed ID
23982732
retrieved
1 December 2016
main subject
proteasome core complex import into nucleus
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1990236
maintenance of protein complex location in cytoplasm
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1990237
Ran GTPase GSP1 YLR293C
1 reference
stated in
GOA release 2020-03-11
Blm10p YFL007W
1 reference
stated in
GOA release 2020-03-11
author name string
Marion H Weberruss
series ordinal
1
0 references
Anca F Savulescu
series ordinal
2
0 references
Julia Jando
series ordinal
3
0 references
Thomas Bissinger
series ordinal
4
0 references
Amnon Harel
series ordinal
5
0 references
Michael H Glickman
series ordinal
6
0 references
Cordula Enenkel
series ordinal
7
0 references
language of work or name
English
0 references
publication date
16 October 2013
0 references
published in
The EMBO Journal
1 reference
stated in
PubMed
PubMed ID
23982732
retrieved
1 December 2016
volume
32
0 references
issue
20
0 references
page(s)
2697-707
0 references
cites work
Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Blm10 protein promotes proteasomal substrate turnover by an active gating mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Sts1 plays a key role in targeting proteasomes to the nucleus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Blm10 binds to pre-activated proteasome core particles with open gate conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Misfolded proteins partition between two distinct quality control compartments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Reversible cytoplasmic localization of the proteasome in quiescent yeast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The bipartite nuclear localization sequence of Rpn2 is required for nuclear import of proteasomal base complexes via karyopherin alphabeta and proteasome functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
PA200, a nuclear proteasome activator involved in DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
20 S proteasomes are imported as precursor complexes into the nucleus of yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
A gated channel into the proteasome core particle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Structural view of the Ran-Importin beta interaction at 2.3 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Structure of 20S proteasome from yeast at 2.4 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The genetic landscape of a cell
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
The nuclear pore complex and nuclear transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
20 March 2017
Structural basis for nuclear import complex dissociation by RanGTP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
7 April 2017
Structural biology of nucleocytoplasmic transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
7 April 2017
Transport into and out of the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
7 April 2017
The 19S cap puzzle: a new jigsaw piece
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Metabolic status rather than cell cycle signals control quiescence entry and exit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Proteasome activator 200: the heat is on...
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Nuclear import of an intact preassembled proteasome particle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Proteasome activators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
The proteasome: overview of structure and functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
PACemakers of proteasome core particle assembly.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Structure of the Blm10-20 S proteasome complex by cryo-electron microscopy. Insights into the mechanism of activation of mature yeast proteasomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Proteasome activator PA200 is required for normal spermatogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Proteasome plasticity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Nucleocytoplasmic transport: taking an inventory
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Expression in yeast of binding regions of karyopherins alpha and beta inhibits nuclear import and cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Possible mechanism of nuclear translocation of proteasomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
29 September 2017
ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome that commit to degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
2 June 2018
Proteasome disassembly and downregulation is correlated with viability during stationary phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
2 June 2018
Import of human and Thermoplasma 20S proteasomes into nuclei of HeLa cells requires functional NLS sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3801435
retrieved
2 June 2018
A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2013.192
retrieved
21 January 2018
New HEAT-like repeat motifs in proteins regulating proteasome structure and function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2013.192
retrieved
21 January 2018
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2013.192
retrieved
21 January 2018
Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2013.192
retrieved
21 January 2018
The import pathway of human and Thermoplasma 20S proteasomes into HeLa cell nuclei is different from that of classical NLS-bearing proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23982732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23982732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Importin β-type nuclear transport receptors have distinct binding affinities for Ran-GTP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23982732
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/EMBOJ.2013.192
0 references
PMCID
3801435
0 references
PubMed ID
23982732
1 reference
stated in
PubMed
PubMed ID
23982732
retrieved
1 December 2016
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