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Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway
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scholarly article
1 reference
stated in
PubMed
PubMed ID
20956557
retrieved
1 December 2016
title
Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway
(English)
1 reference
stated in
PubMed
PubMed ID
20956557
retrieved
1 December 2016
main subject
cell biology
0 references
spliceosome
0 references
U2-type spliceosomal complex subunit CWC22 YGR278W
1 reference
stated in
GOA release 2020-03-11
author
Cheng Soo-chen
series ordinal
6
object named as
Soo-Chen Cheng
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author name string
Tzu-Chi Yeh
series ordinal
1
0 references
Hseuh-Lien Liu
series ordinal
2
0 references
Che-Sheng Chung
series ordinal
3
0 references
Nan-Ying Wu
series ordinal
4
0 references
Yen-Chi Liu
series ordinal
5
0 references
language of work or name
English
0 references
publication date
January 2011
0 references
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
20956557
retrieved
1 December 2016
volume
31
0 references
issue
1
0 references
page(s)
43-53
0 references
cites work
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components
1 reference
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PubMed Central
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20 March 2017
Ntc90 is required for recruiting first step factor Yju2 but not for spliceosome activation
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PubMed Central
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20 March 2017
A novel splicing factor, Yju2, is associated with NTC and acts after Prp2 in promoting the first catalytic reaction of pre-mRNA splicing
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PubMed Central
reference URL
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20 March 2017
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.
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PubMed Central
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20 March 2017
The Prp19p-associated complex in spliceosome activation
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PubMed Central
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20 March 2017
Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast
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PubMed Central
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20 March 2017
Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors
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PubMed Central
reference URL
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20 March 2017
How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing
1 reference
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PubMed Central
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20 March 2017
Functional profiling of the Saccharomyces cerevisiae genome
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PubMed Central
reference URL
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20 March 2017
Characterization of interactions among the Cef1p-Prp19p-associated splicing complex
1 reference
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PubMed Central
reference URL
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20 March 2017
Functional and physical interactions between components of the Prp19p-associated complex
1 reference
stated in
PubMed Central
reference URL
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20 March 2017
The KEGG databases at GenomeNet
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PubMed Central
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20 March 2017
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
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PubMed Central
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20 March 2017
Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p
1 reference
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PubMed Central
reference URL
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20 March 2017
Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
1 reference
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PubMed Central
reference URL
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20 March 2017
Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
Mechanical devices of the spliceosome: motors, clocks, springs, and things
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
Functional association of essential splicing factor(s) with PRP19 in a protein complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
20 March 2017
The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
20 March 2017
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
20 March 2017
Interactions of PRP2 protein with pre-mRNA splicing complexes in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
20 March 2017
The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
The spliceosome: design principles of a dynamic RNP machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
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20 March 2017
Cwc25 is a novel splicing factor required after Prp2 and Yju2 to facilitate the first catalytic reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
The U1, U2 and U5 snRNAs crosslink to the 5' exon during yeast pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Structural and functional analysis of essential pre-mRNA splicing factor Prp19p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Interaction of the yeast DExH-box RNA helicase prp22p with the 3' splice site during the second step of nuclear pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Three recognition events at the branch-site adenine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
A dominant negative mutation in the conserved RNA helicase motif 'SAT' causes splicing factor PRP2 to stall in spliceosomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
SLU7 and a novel activity, SSF1, act during the PRP16-dependent step of yeast pre-mRNA splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Fractionation and characterization of a yeast mRNA splicing extract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
29 September 2017
Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
2 June 2018
Stages in the second reaction of pre-mRNA splicing: the final step is ATP independent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
2 June 2018
Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
2 June 2018
Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
27 November 2018
Isolation of an active step I spliceosome and composition of its RNP core.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
27 November 2018
The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
27 November 2018
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019855
retrieved
27 November 2018
Characterization of the two eIF4A-binding sites on human eIF4G-1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20956557
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Eviction and transplacement of mutant genes in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20956557
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Preparation and fractionation of yeast splicing extract
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20956557
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.00801-10
1 reference
stated in
PubMed
PubMed ID
20956557
retrieved
1 December 2016
PMCID
3019855
0 references
PubMed ID
20956557
1 reference
stated in
PubMed
PubMed ID
20956557
retrieved
1 December 2016
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