(Q28025527)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27367298%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology (English)

1 reference

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17 March 2020

0 references

1 reference

ToxCast

25 May 2024

15

1 reference

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17 March 2020

Christopher M Grulke

4

1 reference

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17 March 2020

John F. Wambaugh

10

1 reference

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17 March 2020

Jayaram Kancherla

12

1 reference

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17 March 2020

Kamel Mansouri

13

1 reference

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17 March 2020

Grace Patlewicz

14

1 reference

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17 March 2020

2

Richard S Judson

1 reference

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17 March 2020

1

Ann M Richard

1 reference

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17 March 2020

3

Keith A Houck

1 reference

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17 March 2020

9

Matthew T Martin

1 reference

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17 March 2020

17

Kevin M Crofton

1 reference

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17 March 2020

18

Russell S Thomas

1 reference

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17 March 2020

11

Thomas B Knudsen

1 reference

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17 March 2020

author name string

Patra Volarath

5

1 reference

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17 March 2020

Inthirany Thillainadarajah

6

1 reference

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17 March 2020

Chihae Yang

7

1 reference

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17 March 2020

James Rathman

8

1 reference

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17 March 2020

Stephen B Little

16

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17 March 2020

publication date

20 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27367298%20AND%20SRC:MED&resulttype=core&format=json

Chemical Research in Toxicology

17 March 2020

published in

2 references

PubMed

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27367298%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

volume

29

1 reference

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17 March 2020

issue

8

1 reference

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17 March 2020

page(s)

1225-1251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27367298%20AND%20SRC:MED&resulttype=core&format=json

The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics

17 March 2020

cites work

0 references

Estimation of synthetic accessibility score of drug-like molecules based on molecular complexity and fragment contributions

1 reference

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Ambiguity of non-systematic chemical identifiers within and between small-molecule databases

2 January 2022

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A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases

2 January 2022

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4 April 2022

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Evaluation of the toxicity forecasting capability of EPA's ToxCast Phase I data: can ToxCast in vitro assays predict carcinogenicity?

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4 April 2022

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In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

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4 April 2022

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Developing scientific confidence in HTS-derived prediction models: lessons learned from an endocrine case study.

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4 April 2022

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Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants

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Towards a gold standard: regarding quality in public domain chemistry databases and approaches to improving the situation

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4 April 2022

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Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).

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Evidence-based toxicology for the 21st century: opportunities and challenges

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4 April 2022

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Apparent activity in high-throughput screening: origins of compound-dependent assay interference

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Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database

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4 April 2022

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Analysis of Pfizer compounds in EPA's ToxCast chemicals-assay space

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4 April 2022

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Toxicity testing in the 21st century beyond environmental chemicals

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4 April 2022

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ACToR — Aggregated Computational Toxicology Resource

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4 April 2022

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Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays

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4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

ToxCast on target: in vitro assays and computer modeling show promise for screening chemicals

1 reference

4 April 2022

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Hazard Evaluation Support System (HESS) for predicting repeated dose toxicity using toxicological categories

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

The toxicity data landscape for environmental chemicals

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4 April 2022

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Critical review of the role of HTS in drug discovery

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Adverse outcome pathway (AOP) development I: strategies and principles

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4 April 2022

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The ToxCast program for prioritizing toxicity testing of environmental chemicals

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4 April 2022

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Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB.

0 references

Lead- and drug-like compounds: the rule-of-five revolution

1 reference

4 April 2022

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Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes

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4 April 2022

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Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity

0 references

Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Use and validation of HT/HC assays to support 21st century toxicity evaluations.

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

High-throughput models for exposure-based chemical prioritization in the ExpoCast project

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

New publicly available chemical query language, CSRML, to support chemotype representations for application to data mining and modeling

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Standardizing benchmark dose calculations to improve science-based decisions in human health assessments

0 references

A quality alert and call for improved curation of public chemistry databases

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Toxicology in the 21st century--working our way towards a visionary reality

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Future of toxicology--predictive toxicology: An expanded view of "chemical toxicity".

0 references

Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

In silico tools for sharing data and knowledge on toxicity and metabolism: derek for windows, meteor, and vitic

0 references

Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System

0 references

The exposure data landscape for manufactured chemicals

1 reference

4 April 2022

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Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.

0 references

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

0 references

Toxicology. Transforming environmental health protection

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4 April 2022

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Improving the human hazard characterization of chemicals: a Tox21 update

0 references

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

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Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

1 reference

4 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet

0 references

Exploring consumer exposure pathways and patterns of use for chemicals in the environment

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

Future challenges to protecting public health from drinking-water contaminants

10 July 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1021/ACS.CHEMRESTOX.6B00135

10.1021/ACS.CHEMRESTOX.6B00135

10 July 2022

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27367298%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference