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Necrotizing enterocolitis: new insights into pathogenesis and mechanisms
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Necrotizing enterocolitis: new insights into pathogenesis and mechanisms
(English)
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stated in
PubMed
main subject
pathogenesis
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based on heuristic
inferred from title
necrotizing enterocolitis
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based on heuristic
inferred from title
author name string
Diego F. Niño
series ordinal
1
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Crossref
Chhinder P. Sodhi
series ordinal
2
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Crossref
David J. Hackam
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
October 2016
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stated in
PubMed
published in
Nature Reviews Gastroenterology & Hepatology
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stated in
PubMed
volume
13
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stated in
PubMed
issue
10
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PubMed
page(s)
590-600
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PubMed
cites work
Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals
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The Role of Immunonutrients in the Prevention of Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants
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Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
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Probiotics and necrotizing enterocolitis
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Formula versus donor breast milk for feeding preterm or low birth weight infants
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Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
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Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis
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Peritoneal drainage versus laparotomy as initial surgical treatment for perforated necrotizing enterocolitis or spontaneous intestinal perforation in preterm low birth weight infants
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Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis in Very Low-Birth-Weight Infants
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Prevention of Necrotizing Enterocolitis Through Manipulation of the Intestinal Microbiota of the Premature Infant
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Development of the Neonatal Intestinal Microbiome and Its Association With Necrotizing Enterocolitis.
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Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
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Outborns or Inborns: Where Are the Differences? A Comparison Study of Very Preterm Neonatal Intensive Care Unit Infants Cared for in Australia and New Zealand and in Canada
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Risk factors associated with postnecrotizing enterocolitis strictures in infants
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Sonographic markers associated with adverse neonatal outcomes among fetuses with gastroschisis: an 11-year, single-center review
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The Role of Bacteria in Necrotizing Enterocolitis: Understanding the Forest for the Trees
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Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis
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Intestinal microbiota and its relationship with necrotizing enterocolitis.
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SIGIRR genetic variants in premature infants with necrotizing enterocolitis
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Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor
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Outcomes and costs of surgical treatments of necrotizing enterocolitis
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Serious congenital heart disease and necrotizing enterocolitis in very low birth weight neonates
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Association of neonatal necrotizing enterocolitis with myeloid differentiation-2 and GM2 activator protein genetic polymorphisms
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Intestinal fatty acid-binding protein as a diagnostic marker for complicated and uncomplicated necrotizing enterocolitis: a prospective cohort study.
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Intestinal fatty acid-binding protein levels in Necrotizing Enterocolitis correlate with extent of necrotic bowel: results from a multicenter study
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Low birthweight, gestational age, need for surgical intervention and gram-negative bacteraemia predict intestinal failure following necrotising enterocolitis
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Lactoferrin and neonatology - role in neonatal sepsis and necrotizing enterocolitis: present, past and future
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Noninvasive biomarkers of necrotizing enterocolitis
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The use of laboratory biomarkers for surveillance, diagnosis and prediction of clinical outcomes in neonatal sepsis and necrotising enterocolitis
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Pathogenesis of necrotizing enterocolitis: modeling the innate immune response.
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Complex gastroschisis is a different entity to simple gastroschisis affecting morbidity and mortality-a systematic review and meta-analysis
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29 September 2017
Necrotizing enterocolitis: a clinical review on diagnostic biomarkers and the role of the intestinal microbiota.
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29 September 2017
Cochrane in context: probiotics for prevention of necrotizing enterocolitis in preterm infants
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29 September 2017
Probiotics for prevention of necrotizing enterocolitis in preterm infants.
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29 September 2017
Mucosa-associated bacterial diversity in necrotizing enterocolitis
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Gastric residual evaluation in preterm neonates: a useful monitoring technique or a hindrance?
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The impact of prenatal and neonatal infection on neurodevelopmental outcomes in very preterm infants.
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29 September 2017
Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis
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Evidence-based feeding strategies before and after the development of necrotizing enterocolitis.
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29 September 2017
Lactobacillus reuteri DSM 17938 differentially modulates effector memory T cells and Foxp3+ regulatory T cells in a mouse model of necrotizing enterocolitis
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Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges.
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Lactobacillus rhamnosus HN001 decreases the severity of necrotizing enterocolitis in neonatal mice and preterm piglets: evidence in mice for a role of TLR9.
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29 September 2017
Cytokines associated with necrotizing enterocolitis in extremely-low-birth-weight infants
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29 September 2017
Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression
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29 September 2017
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
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29 September 2017
Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
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Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants.
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29 September 2017
Amniotic fluid-borne hepatocyte growth factor protects rat pups against experimental necrotizing enterocolitis
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29 September 2017
FoxP3⁺ regulatory T cells attenuate experimental necrotizing enterocolitis
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29 September 2017
Toll-like receptor regulation of intestinal development and inflammation in the pathogenesis of necrotizing enterocolitis
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Heparin-binding EGF-like growth factor (HB-EGF) therapy for intestinal injury: Application and future prospects
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29 September 2017
Royal Australasia of Surgeons Guest Lecture. Necrotizing enterocolitis: prevention, treatment, and outcome
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29 September 2017
Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis.
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29 September 2017
Biomarkers of necrotising enterocolitis
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A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants
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29 September 2017
Necrotizing enterocolitis: contemporary management and outcomes
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29 September 2017
Feeding intolerance in the preterm infant
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29 September 2017
Erythropoietin protects epithelial cells from excessive autophagy and apoptosis in experimental neonatal necrotizing enterocolitis
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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29 September 2017
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Breast-feeding improves gut maturation compared with formula feeding in preterm babies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Glutamine downregulates TLR-2 and TLR-4 expression and protects intestinal tract in preterm neonatal rats with necrotizing enterocolitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Enteral L-arginine supplementation for prevention of necrotizing enterocolitis in very low birth weight neonates: a double-blind randomized pilot study of efficacy and safety.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
HB-EGF promotes intestinal restitution by affecting integrin-extracellular matrix interactions and intercellular adhesions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Deep 16S rRNA metagenomics and quantitative PCR analyses of the premature infant fecal microbiota.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Incidence and Timing of Presentation of Necrotizing Enterocolitis in Preterm Infants
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
The risk of necrotizing enterocolitis after indomethacin tocolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
Mortality of necrotizing enterocolitis expressed by birth weight categories
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Peritoneal drainage or laparotomy for neonatal bowel perforation? A randomized controlled trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Necrotising enterocolitis hospitalisations among neonates in the United States
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Heparin-binding epidermal growth factor-like growth factor reduces intestinal apoptosis in neonatal rats with necrotizing enterocolitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Increased incidence of necrotizing enterocolitis in premature infants born to HIV-positive mothers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Necrotizing Enterocolitis: Assessment of Bowel Viability with Color Doppler US
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Epidemiology of necrotizing enterocolitis--Part II: Risks and susceptibility of premature infants during the surfactant era: a regional study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Variations in incidence of necrotizing enterocolitis in Canadian neonatal intensive care units
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Necrotizing enterocolitis and neurodevelopmental outcome in extremely low birth weight infants <1000 g.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Gastric residuals and their relationship to necrotizing enterocolitis in very low birth weight infants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
Lower prevalence of IL-4 receptor α-chain gene 1902G variant in very-low-birth-weight infants with necrotizing enterocolitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
Genetic variants of the interleukin-18 promoter region (-607) influence the course of necrotising enterocolitis in very low birth weight neonates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Trends in mortality and morbidity for very low birth weight infants, 1991-1999.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
Arginine supplementation prevents necrotizing enterocolitis in the premature infant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
retrieved
27 November 2018
Heparin-Binding EGF-Like Growth Factor Down Regulates Proinflammatory Cytokine-Induced Nitric Oxide and Inducible Nitric Oxide Synthase Production in Intestinal Epithelial Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Impact of necrotizing enterocolitis on length of stay and hospital charges in very low birth weight infants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5124124
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27 November 2018
Necrotizing enterocolitis
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
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31 March 2020
Non-invasive markers for early diagnosis and determination of the severity of necrotizing enterocolitis
1 reference
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Crossref
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31 March 2020
Prospective evaluation of the impact of sonography on the management and surgical intervention of neonates with necrotizing enterocolitis
1 reference
stated in
Crossref
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31 March 2020
Platelet-activating factor in infants at risk for necrotizing enterocolitis
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
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31 March 2020
An Exclusively Human Milk-Based Diet Is Associated with a Lower Rate of Necrotizing Enterocolitis than a Diet of Human Milk and Bovine Milk-Based Products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Necrotizing enterocolitis among neonates in the United States
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Exposure to HIV and antiretroviral medication as a potential cause of necrotizing enterocolitis in term neonates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
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31 March 2020
Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Heparin-binding EGF-like growth factor is present in human amniotic fluid and breast milk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Epidermal growth factor and necrotizing enterocolitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Recurrent necrotizing enterocolitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNRGASTRO.2016.119
retrieved
31 March 2020
Presence of platelet-activating factor-acetylhydrolase in milk
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27534694
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NRGASTRO.2016.119
0 references
PMC publication ID
5124124
1 reference
stated in
PubMed
PubMed publication ID
27534694
1 reference
stated in
PubMed
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