(Q55052541)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Maria T Abreu

series ordinal

1

1 reference

http://europepmc.org/abstract/MED/20098461

16 June 2018

publication date

1 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

131-144

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

The gastrointestinal tract stem cell niche

17 January 2020

cites work

1 reference

Human CD8+ intraepithelial lymphocytes: a unique model to study the regulation of effector cytotoxic T lymphocytes in tissue

31 March 2020

1 reference

Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

31 March 2020

1 reference

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

31 March 2020

1 reference

Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice.

31 March 2020

1 reference

TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium.

31 March 2020

1 reference

Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism

31 March 2020

1 reference

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

31 March 2020

1 reference

Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide

31 March 2020

1 reference

Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells

31 March 2020

1 reference

Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis.

31 March 2020

1 reference

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

31 March 2020

1 reference

Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium.

31 March 2020

1 reference

PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 gene

31 March 2020

1 reference

Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex

31 March 2020

1 reference

Th2 cytokines down-regulate TLR expression and function in human intestinal epithelial cells

31 March 2020

1 reference

Cytokine-mediated control of lipopolysaccharide-induced activation of small intestinal epithelial cells

31 March 2020

1 reference

Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine

31 March 2020

1 reference

Surface expression of Toll-like receptor 9 is upregulated on intestinal epithelial cells in response to pathogenic bacterial DNA.

31 March 2020

1 reference

Enteroendocrine cells: neglected players in gastrointestinal disorders?

31 March 2020

1 reference

Enteroendocrine cells express functional Toll-like receptors

31 March 2020

1 reference

Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion

31 March 2020

1 reference

TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium

31 March 2020

1 reference

Evidence for an innate immune response in the immature human intestine: toll-like receptors on fetal enterocytes

31 March 2020

1 reference

Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

31 March 2020

1 reference

Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation.

31 March 2020

1 reference

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

31 March 2020

1 reference

In vitro and ex vivo activation of the TLR5 signaling pathway in intestinal epithelial cells by a commensal Escherichia coli strain

31 March 2020

1 reference

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

31 March 2020

1 reference

MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.

31 March 2020

1 reference

Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium

31 March 2020

1 reference

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

31 March 2020

1 reference

TLR9 is localized in the endoplasmic reticulum prior to stimulation

31 March 2020

1 reference

Immunostimulatory oligonucleotides inhibit colonic proinflammatory cytokine production in ulcerative colitis

31 March 2020

1 reference

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

31 March 2020

1 reference

Regulatory molecules required for nucleotide-sensing Toll-like receptors

31 March 2020

1 reference

Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells

31 March 2020

1 reference

Intracellular Recognition of Lipopolysaccharide by Toll-like Receptor 4 in Intestinal Epithelial Cells

31 March 2020

1 reference

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

31 March 2020

1 reference

Negative regulation of toll-like receptor-mediated signaling by Tollip

31 March 2020

1 reference

Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

31 March 2020

1 reference

Expression and function of toll-like receptor 8 and Tollip in colonic epithelial cells from patients with inflammatory bowel disease

31 March 2020

1 reference

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

31 March 2020

1 reference

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

31 March 2020

1 reference

The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis.

31 March 2020

1 reference

Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis.

31 March 2020

1 reference

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

31 March 2020

1 reference

Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance

31 March 2020

1 reference

Current view: intestinal stem cells and signaling

31 March 2020

1 reference

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

31 March 2020

1 reference

31 March 2020

1 reference

Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

31 March 2020

1 reference

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

31 March 2020

1 reference

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

31 March 2020

1 reference

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

31 March 2020

1 reference

MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis

31 March 2020

1 reference

TLR signaling in the gut in health and disease

31 March 2020

1 reference

Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

31 March 2020

1 reference

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

31 March 2020

1 reference

A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease

31 March 2020

1 reference

Regulation of colonic epithelial repair in mice by Toll-like receptors and hyaluronic acid

31 March 2020

1 reference

Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine.

31 March 2020

1 reference

Innate immune signaling by Toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors

31 March 2020

1 reference

X. Trefoil peptide and EGF receptor/ligand transgenic mice

31 March 2020

1 reference

Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

31 March 2020

1 reference

Flagellin treatment protects against chemicals, bacteria, viruses, and radiation.

31 March 2020

1 reference

Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

31 March 2020

1 reference

Activation of toll-like receptor 3 protects against DSS-induced acute colitis

31 March 2020

1 reference

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

31 March 2020

1 reference

Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.

31 March 2020

1 reference

Toll-like receptor 9-induced type I IFN protects mice from experimental colitis

31 March 2020

1 reference

Flagellin suppresses epithelial apoptosis and limits disease during enteric infection

31 March 2020

1 reference

TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression

31 March 2020

1 reference

Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways.

31 March 2020

1 reference

Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response

31 March 2020

1 reference

Comparison of late rectal toxicity from conventional versus three-dimensional conformal radiotherapy for prostate cancer: analysis of clinical and dosimetric factors

31 March 2020

1 reference

The Gut Microbiota Predispose to the Pathophysiology of Acute Postradiotherapy Diarrhea

31 March 2020

1 reference

Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism.

31 March 2020

1 reference

TNFR1 mediates the radioprotective effects of lipopolysaccharide in the mouse intestine

31 March 2020

1 reference

An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models

31 March 2020

1 reference

Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin

31 March 2020

1 reference

Taking toll: lipid A mimetics as adjuvants and immunomodulators

31 March 2020

1 reference

Necrotizing enterocolitis--bench to bedside: novel and emerging strategies

31 March 2020

1 reference

The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis

31 March 2020

1 reference

A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.

31 March 2020

1 reference

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

31 March 2020

1 reference

Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis

31 March 2020

1 reference

Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitis

31 March 2020

1 reference

Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis

31 March 2020

1 reference

Expression of TLR-2, TLR-4, NOD2 and pNF-kappaB in a neonatal rat model of necrotizing enterocolitis.

31 March 2020

1 reference

Oral probiotics prevent necrotizing enterocolitis in very low birth weight preterm infants: a multicenter, randomized, controlled trial

31 March 2020

1 reference

Molecular analysis of commensal host-microbial relationships in the intestine

31 March 2020

1 reference

Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

31 March 2020

1 reference

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

31 March 2020

1 reference

Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells

31 March 2020

1 reference

Mammalian defensins in the antimicrobial immune response

31 March 2020

1 reference

Angiogenins: a new class of microbicidal proteins involved in innate immunity

31 March 2020

1 reference

Symbiotic bacteria direct expression of an intestinal bactericidal lectin

31 March 2020

1 reference

Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli

31 March 2020

1 reference

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

31 March 2020

1 reference

Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis

31 March 2020

1 reference

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

31 March 2020

1 reference

MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection

31 March 2020

1 reference

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

31 March 2020

1 reference

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

31 March 2020

1 reference

The immune geography of IgA induction and function

31 March 2020

1 reference

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

31 March 2020

1 reference

TACI and BAFF-R mediate isotype switching in B cells

31 March 2020

1 reference

Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria

31 March 2020

1 reference

Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement

31 March 2020

1 reference

Epithelial NEMO links innate immunity to chronic intestinal inflammation

31 March 2020

1 reference

Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis

31 March 2020

1 reference

Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

31 March 2020

1 reference

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

31 March 2020

1 reference

Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine.

31 March 2020

1 reference

IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis

31 March 2020

1 reference

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

31 March 2020

1 reference

Modulation of dendritic cell phenotype and functionin anin vitromodel of the intestinal epithelium

31 March 2020

1 reference

Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway

31 March 2020

1 reference

Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.

31 March 2020

1 reference

Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency

31 March 2020

1 reference

Colorectal cancer and genetic alterations in the Wnt pathway

31 March 2020

1 reference

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

31 March 2020

1 reference

APC mutations occur early during colorectal tumorigenesis

31 March 2020

1 reference

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

31 March 2020

1 reference

A two-step model for colon adenoma initiation and progression caused by APC loss

31 March 2020

1 reference

Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis.

31 March 2020

1 reference

At the crossroads of inflammation and cancer

31 March 2020

1 reference

Inflammatory bowel disease: a model of chronic inflammation-induced cancer

31 March 2020

1 reference

Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family

31 March 2020

1 reference

Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer

31 March 2020

1 reference

Toll-like receptors on tumor cells facilitate evasion of immune surveillance

31 March 2020

1 reference

Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation

31 March 2020

1 reference

Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria.

31 March 2020

1 reference

Strategic compartmentalization of Toll-like receptor 4 in the mouse gut

31 March 2020

1 reference

Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.

31 March 2020

1 reference

IL-10 gene-deficient mice lack TGF-beta/Smad signaling and fail to inhibit proinflammatory gene expression in intestinal epithelial cells after the colonization with colitogenic Enterococcus faecalis.

31 March 2020

1 reference

Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis.

31 March 2020

1 reference

Regulation of toll-like receptors in intestinal epithelial cells by stress and Toxoplasma gondii infection

31 March 2020

1 reference

Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria.

31 March 2020

1 reference

Absence of Toll-like receptor 4 explains endotoxin hyporesponsiveness in human intestinal epithelium

31 March 2020

1 reference

Recognition of double-stranded RNA by TLR3 induces severe small intestinal injury in mice

31 March 2020

1 reference

Regulation of Toll-like receptor 4 expression in mouse colon by macrophage migration inhibitory factor

31 March 2020

1 reference

Regulation of serum amyloid A3 (SAA3) in mouse colonic epithelium and adipose tissue by the intestinal microbiota

31 March 2020

1 reference

Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier

31 March 2020

1 reference

Microbial pattern recognition receptors mediate M-cell uptake of a gram-negative bacterium

31 March 2020

1 reference

Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy.

31 March 2020

1 reference

Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo.

31 March 2020

1 reference

Degranulation of paneth cells via toll-like receptor 9.

31 March 2020

1 reference

Deletion of TLR5 results in spontaneous colitis in mice

31 March 2020

1 reference

12 December 2020

Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. A comparison of germ-free and conventional mice

1 reference

12 December 2020

Signal integration following Toll-like receptor triggering.

1 reference

12 December 2020

Does necrotising enterocolitis impact the neurodevelopmental and growth outcomes in preterm infants with birthweight < or =1250 g?

1 reference

12 December 2020

Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitis

1 reference

12 December 2020

Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-kappaB-independent pathway

1 reference

12 December 2020

Inflammatory breast cancer: the experience of the surveillance, epidemiology, and end results (SEER) program

1 reference

12 December 2020

Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status.

1 reference

12 December 2020

Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta

1 reference

12 December 2020

TLR signaling at the intestinal epithelial interface

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI2707

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098461%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference