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A century of cholesterol and coronaries: from plaques to genes to statins
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title
A century of cholesterol and coronaries: from plaques to genes to statins
(English)
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author name string
Joseph L. Goldstein
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1
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Michael S. Brown
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2
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English
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publication date
26 March 2015
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published in
Cell
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volume
161
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issue
1
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PubMed
page(s)
161-72
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PubMed
cites work
The LDL receptor
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PubMed Central
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20 March 2017
Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL
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20 March 2017
Structure of a site-2 protease family intramembrane metalloprotease
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20 March 2017
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation
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20 March 2017
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins
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20 March 2017
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
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20 March 2017
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
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20 March 2017
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
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Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
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Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
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SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent
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Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol
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NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor
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Low-density lipoprotein cholesterol-lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypercholesterolemia: the Reduction of LDL-C with PCSK9 In
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Oxidized low-density lipoprotein and atherosclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
The 1964 Nobel Prize for the discovery of the biosynthesis of cholesterol.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
A PCSK9 missense variant associated with a reduced risk of early-onset myocardial infarction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Biomedicine. Lowering LDL--not only how low, but how long?
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Lessons from serum cholesterol studies in Japan, Hawaii and Los Angeles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Purification of the low density lipoprotein receptor, an acidic glycoprotein of 164,000 molecular weight
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4525717
retrieved
27 November 2018
Influence of lovastatin therapy on metabolism of low density lipoproteins in mixed hyperlipidaemia
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Combating the epidemic of heart disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neonatal diagnosis of familial type-II hyperlipoproteinaemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lovastatin therapy in receptor-negative homozygous familial hypercholesterolemia: Lack of effect on low-density lipoprotein concentrations or turnover
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The distribution and composition of serum lipoproteins in eighteen animals
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
THE INHERITANCE OF ESSENTIAL FAMILIAL HYPERCHOLESTEROLEMIA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hyperlipoproteinemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Statins for primary prevention of coronary artery disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25815993
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELL.2015.01.036
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
566058
Fatcat ID
release_pnx2pbgk5jdxvi65oswb4ybgd4
0 references
OpenCitations bibliographic resource ID
566058
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
566058
PMC publication ID
4525717
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
566058
PubMed publication ID
25815993
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
566058
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