(Q28087233)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Leptin applications in 2015: what have we learned about leptin and obesity? (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

Christos Socrates Mantzoros

23 February 2020

series ordinal

3

object named as

Christos S Mantzoros

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Anna Gavrieli

series ordinal

2

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

1 reference

1 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Endocrinology, Diabetes and Obesity

23 February 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

22

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

353-359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

Obesity genetics in mouse and human: back and forth, and back again

23 February 2020

cites work

1 reference

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20 March 2017

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Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals

20 March 2017

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Narrative review: the role of leptin in human physiology: emerging clinical applications

20 March 2017

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20 March 2017

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The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

20 March 2017

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Positional cloning of the mouse obese gene and its human homologue

20 March 2017

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

20 March 2017

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

20 March 2017

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20 March 2017

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20 March 2017

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

7 April 2017

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Effects of the obese gene product on body weight regulation in ob/ob mice

7 April 2017

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Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance

7 April 2017

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FTO is necessary for the induction of leptin resistance by high-fat feeding

29 September 2017

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Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice.

29 September 2017

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Possible involvement of 15-deoxy-Δ(12,14) -prostaglandin J2 in the development of leptin resistance

29 September 2017

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Leptin and insulin act on POMC neurons to promote the browning of white fat.

29 September 2017

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Liraglutide, leptin and their combined effects on feeding: additive intake reduction through common intracellular signalling mechanisms

29 September 2017

1 reference

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Leptin replacement therapy for the treatment of non-HAART associated lipodystrophy syndromes: a meta-analysis into the effects of leptin on metabolic and hepatic endpoints.

29 September 2017

1 reference

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Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure.

29 September 2017

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Leptin in congenital and HIV-associated lipodystrophy.

29 September 2017

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Metabolic adaptation following massive weight loss is related to the degree of energy imbalance and changes in circulating leptin

29 September 2017

1 reference

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Leptin treatment: facts and expectations.

29 September 2017

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PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding

29 September 2017

1 reference

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Recombinant human leptin does not alter gut hormone levels after gastric bypass but may attenuate sweet cravings

29 September 2017

1 reference

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Effects of chronic leptin infusion on subsequent body weight and composition in mice: Can body weight set point be reset?

29 September 2017

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Obesity and mortality: are the risks declining? Evidence from multiple prospective studies in the United States

29 September 2017

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Pluronic modified leptin with increased systemic circulation, brain uptake and efficacy for treatment of obesity

29 September 2017

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Long-term stabilization effects of leptin on brain functions in a leptin-deficient patient

29 September 2017

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Leptin at the intersection of neuroendocrinology and metabolism: current evidence and therapeutic perspectives.

29 September 2017

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29 September 2017

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Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity

29 September 2017

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Effects of reduced weight maintenance and leptin repletion on functional connectivity of the hypothalamus in obese humans

29 September 2017

1 reference

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Randomized double-blind placebo-controlled study of leptin administration after gastric bypass

29 September 2017

1 reference

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The liver diseases of lipodystrophy: the long-term effect of leptin treatment

29 September 2017

1 reference

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Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia

29 September 2017

1 reference

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Molecular mechanisms of central leptin resistance in obesity

29 September 2017

1 reference

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Effect of leptin administration on myelination in ob/ob mouse cerebrum after birth

29 September 2017

1 reference

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Functional magnetic resonance imaging analysis of food-related brain activity in patients with lipodystrophy undergoing leptin replacement therapy

29 September 2017

1 reference

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Leptin and leptin receptor-related monogenic obesity

29 September 2017

1 reference

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Role of the blood-brain barrier in the evolution of feeding and cognition

29 September 2017

1 reference

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Optimizing bone health in anorexia nervosa and hypothalamic amenorrhea: new trials and tribulations.

29 September 2017

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Leptin reverses declines in satiation in weight-reduced obese humans

29 September 2017

1 reference

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Comparison of efficacy and safety of leptin replacement therapy in moderately and severely hypoleptinemic patients with familial partial lipodystrophy of the Dunnigan variety

29 September 2017

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Repositioning leptin as a therapy for Alzheimer's disease

29 September 2017

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Clinical effects of long-term metreleptin treatment in patients with lipodystrophy

29 September 2017

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Novel strategy for the use of leptin for obesity therapy

29 September 2017

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Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin

29 September 2017

1 reference

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The fall in leptin concentration is a major determinant of the metabolic adaptation induced by caloric restriction independently of the changes in leptin circadian rhythms

29 September 2017

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Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet.

29 September 2017

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Leptin is an effective treatment for hypothalamic amenorrhea.

29 September 2017

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Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans

29 September 2017

1 reference

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Leptin deficiency: clinical implications and opportunities for therapeutic interventions

29 September 2017

1 reference

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Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states: regulation by gender and adiposity

29 September 2017

1 reference

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Leptin reverses weight loss-induced changes in regional neural activity responses to visual food stimuli

29 September 2017

1 reference

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Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy

29 September 2017

1 reference

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Leptin regulates striatal regions and human eating behavior

29 September 2017

1 reference

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Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy

29 September 2017

1 reference

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Leptin: a potential novel antidepressant

29 September 2017

1 reference

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Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight

29 September 2017

1 reference

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Anatomy and regulation of the central melanocortin system

29 September 2017

1 reference

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Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults

29 September 2017

1 reference

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Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy

29 September 2017

1 reference

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Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

29 September 2017

1 reference

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Exercise and female adolescents: effects on the reproductive and skeletal systems.

29 September 2017

1 reference

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A role for leptin in brain development

29 September 2017

1 reference

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The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice

29 September 2017

1 reference

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Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake

29 September 2017

1 reference

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Increased obese mRNA expression in omental fat cells from massively obese humans

29 September 2017

1 reference

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Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

29 September 2017

1 reference

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Phosphodiesterase-3B-cAMP pathway of leptin signalling in the hypothalamus is impaired during the development of diet-induced obesity in FVB/N mice.

29 September 2017

1 reference

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Imbalance of leptin pathway and hypothalamus synaptic plasticity markers are associated with stress-induced depression in rats

2 June 2018

1 reference

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Efficacy of leptin therapy in the different forms of human lipodystrophy

2 June 2018

1 reference

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Nutritional and endocrine-metabolic aberrations in women with functional hypothalamic amenorrhea

2 June 2018

1 reference

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Altered neuroanatomical organization in the central nervous system of the genetically obese (ob/ob) mouse

2 June 2018

1 reference

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PASylation of Murine Leptin Leads to Extended Plasma Half-Life and Enhanced in Vivo Efficacy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Changes in leptin and peptide YY do not explain the greater-than-predicted decreases in resting energy expenditure after weight loss

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Estradiol prevents fat accumulation and overcomes leptin resistance in female high-fat diet mice.

27 November 2018

1 reference

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Novel LEPR mutations in obese Pakistani children identified by PCR-based enrichment and next generation sequencing.

27 November 2018

1 reference

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Leptin therapy in a congenital leptin-deficient patient leads to acute and long-term changes in homeostatic, reward, and food-related brain areas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Resistance to leptin-replacement therapy in Berardinelli-Seip congenital lipodystrophy: an immunological origin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Metabolic correction induced by leptin replacement treatment in young children with Berardinelli-Seip congenital lipoatrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Long-term efficacy of leptin replacement in patients with generalized lipodystrophy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

The long-term effect of recombinant methionyl human leptin therapy on hyperandrogenism and menstrual function in female and pituitary function in male and female hypoleptinemic lipodystrophic patients

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Changes in body composition in patients with severe lipodystrophy after leptin replacement therapy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Human immunodeficiency virus type 1-related lipoatrophy and lipohypertrophy are associated with serum concentrations of leptin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Effect of leptin replacement on pituitary hormone regulation in patients with severe lipodystrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Leptin-replacement therapy for lipodystrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Leptin in relation to resumption of menses in women with anorexia nervosa.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

A leptin missense mutation associated with hypogonadism and morbid obesity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Women with functional hypothalamic amenorrhea but not other forms of anovulation display amplified cortisol concentrations.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Hypoleptinemia in women athletes: absence of a diurnal rhythm with amenorrhea

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4610373

Decreased serum leptin in bulimia nervosa

27 November 2018

1 reference

12 December 2020

Pharmacokinetics of human leptin in mice and rhesus monkeys

1 reference

12 December 2020

Glucose utilization and glucose transporter proteins GLUT-1 and GLUT-3 in brains of diabetic (db/db) mice

1 reference

12 December 2020

Adult-onset amenorrhea: a study of 262 patients

1 reference

12 December 2020

Seven novel deleterious LEPR mutations found in early-onset obesity: a ΔExon6-8 shared by subjects from Reunion Island, France, suggests a founder effect

1 reference

12 December 2020

10.1097/MED.0000000000000184

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26313897%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2 references