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Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma
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scholarly article
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stated in
PubMed
review article
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stated in
Europe PubMed Central
title
Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma
(English)
1 reference
stated in
PubMed
main subject
glioblastoma
1 reference
based on heuristic
inferred from title
author name string
Emily Padfield
series ordinal
1
1 reference
stated in
Crossref
Hayley P. Ellis
series ordinal
2
1 reference
stated in
Crossref
Kathreena M. Kurian
series ordinal
3
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stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
29 January 2015
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stated in
PubMed
published in
Frontiers in Oncology
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stated in
Crossref
volume
5
1 reference
stated in
PubMed
page(s)
5
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stated in
PubMed
cites work
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Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations
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EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma
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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
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The natural history of EGFR and EGFRvIII in glioblastoma patients
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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
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The efficacy and safety of EGFR inhibitor monotherapy in non-small cell lung cancer: a systematic review
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29 September 2017
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
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29 September 2017
Targeted induction of apoptosis in glioblastoma multiforme cells by an MRP3-specific TRAIL fusion protein in vitro
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MicroRNA in Human Glioma
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29 September 2017
Nimotuzumab treatment of malignant gliomas
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29 September 2017
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
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29 September 2017
EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.
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29 September 2017
Activation of multiple ERBB family receptors mediates glioblastoma cancer stem-like cell resistance to EGFR-targeted inhibition.
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29 September 2017
Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors
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29 September 2017
Targeting the EGFR-family for therapy: biological challenges and clinical perspective.
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29 September 2017
Transferrin antibodies into the brain
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29 September 2017
Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance
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29 September 2017
Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells
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29 September 2017
Heterogeneity maintenance in glioblastoma: a social network
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29 September 2017
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma
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29 September 2017
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
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29 September 2017
RNA interference therapy for glioblastoma
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29 September 2017
Emerging concepts for the treatment of hematological malignancies with therapeutic monoclonal antibodies.
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29 September 2017
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
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29 September 2017
EGFRvIII-targeted vaccination therapy of malignant glioma
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29 September 2017
Therapeutic inhibition of the epidermal growth factor receptor in high-grade gliomas: where do we stand?
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29 September 2017
The EGFRvIII variant in glioblastoma multiforme
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29 September 2017
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma
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29 September 2017
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Uncovering therapeutic targets for glioblastoma: a systems biology approach
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29 September 2017
Monoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surface.
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29 September 2017
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma
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29 September 2017
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
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29 September 2017
PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors
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29 September 2017
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
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29 September 2017
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
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29 September 2017
IkappaBalphaM suppresses angiogenesis and tumorigenesis promoted by a constitutively active mutant EGFR in human glioma cells
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29 September 2017
Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
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29 September 2017
Radioimmunotherapy as a novel treatment regimen: 125I-labeled monoclonal antibody 425 in the treatment of high-grade brain gliomas
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29 September 2017
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Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas
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2 June 2018
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27 November 2018
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27 November 2018
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27 November 2018
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme
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27 November 2018
A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation.
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27 November 2018
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27 November 2018
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27 November 2018
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27 November 2018
Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival.
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27 November 2018
Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Activity of anti-epidermal growth factor receptor monoclonal antibody C225 against glioblastoma multiforme.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Function of aberrant EGFR in malignant gliomas.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Inhibition of tumor growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310282
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27 November 2018
Phase I/II trial of custirsen (OGX-011), an inhibitor of clusterin, in combination with a gemcitabine and platinum regimen in patients with previously untreated advanced non-small cell lung cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25688333
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FONC.2015.00005
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2150219
OpenCitations bibliographic resource ID
2150219
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2150219
PMCID
4310282
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2150219
PubMed ID
25688333
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2150219
ResearchGate publication ID
272512073
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