(Q33725972)

28 July 2017

title

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. (English)

1 reference

28 July 2017

Tomoyuki Koga

5

0 references

Frank B Furnari

object named as

Frank B Furnari

24

0 references

Timothy F. Cloughesy

18

object named as

Timothy F Cloughesy

1 reference

28 July 2017

21

Harley I Kornblum

1 reference

28 July 2017

17

Stanley F Nelson

1 reference

28 July 2017

David A Nathanson

1

1 reference

28 July 2017

Beatrice Gini

2

1 reference

28 July 2017

Jack Mottahedeh

3

1 reference

28 July 2017

Koppany Visnyei

4

1 reference

28 July 2017

German Gomez

6

1 reference

28 July 2017

Ascia Eskin

7

1 reference

28 July 2017

Kiwook Hwang

8

1 reference

28 July 2017

Jun Wang

9

1 reference

28 July 2017

Kenta Masui

10

1 reference

28 July 2017

Andres Paucar

11

1 reference

28 July 2017

Huijun Yang

12

1 reference

28 July 2017

Minori Ohashi

13

1 reference

28 July 2017

Shaojun Zhu

14

1 reference

28 July 2017

Jill Wykosky

15

1 reference

28 July 2017

Rachel Reed

16

1 reference

28 July 2017

C David James

19

1 reference

28 July 2017

P Nagesh Rao

20

1 reference

28 July 2017

James R Heath

22

1 reference

28 July 2017

Webster K Cavenee

23

1 reference

28 July 2017

Paul S Mischel

25

1 reference

28 July 2017

language of work or name

English

0 references

publication date

5 December 2013

1 reference

28 July 2017

number of pages

5

1 reference

based on heuristic

inferred from page(s)

published in

Science

1 reference

28 July 2017

volume

343

1 reference

28 July 2017

issue

6166

1 reference

28 July 2017

page(s)

72-76

1 reference

The somatic genomic landscape of glioblastoma

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

21 June 2018

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Circumventing cancer drug resistance in the era of personalized medicine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Converting cancer therapies into cures: lessons from infectious diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Heterogeneity maintenance in glioblastoma: a social network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Robust detection of EGFR copy number changes and EGFR variant III: technical aspects and relevance for glioma diagnostics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Epidermal growth factor receptor inhibitors in neuro-oncology: hopes and disappointments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Cancerous stem cells can arise from pediatric brain tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Tumor antigens in astrocytic gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Double minute chromosomes and homogeneously staining regions in tumors taken directly from patients versus in human tumor cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Elimination of extrachromosomally amplified MYC genes from human tumor cells reduces their tumorigenicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Gene amplification and drug resistance in cultured murine cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1241328

Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1241328

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1241328

Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049335

Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24310612

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24310612

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1241328

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference