(Q39314446)

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EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms.

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7 February 2020

EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22797070%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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Catherine A Del Vecchio

1

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7 February 2020

Otto Hannes Vogel

3

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7 February 2020

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7 February 2020

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C P Giacomini

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7 February 2020

K C Jensen

4

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7 February 2020

A Merlo

6

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7 February 2020

J R Pollack

7

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7 February 2020

A J Wong

8

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7 February 2020

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16 July 2012

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7 February 2020

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7 February 2020

32

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7 February 2020

2670-2681

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7 February 2020

21

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7 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2012.280

0 references

Prevalence estimates for primary brain tumors in the United States by age, gender, behavior, and histology

1 reference

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21 January 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors

1 reference

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

1 reference

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Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer

1 reference

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Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.280

21 January 2018

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.280

21 January 2018

Identification of human brain tumour initiating cells

1 reference

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21 January 2018

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

1 reference

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21 January 2018

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

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21 January 2018

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

1 reference

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21 January 2018

Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

1 reference

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21 January 2018

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

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21 January 2018

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells

1 reference

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21 January 2018

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

1 reference

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21 January 2018

Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas

1 reference

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21 January 2018

Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma.

1 reference

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21 January 2018

Predominant expression of mutant EGFR (EGFRvIII) is rare in primary glioblastomas.

1 reference

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21 January 2018

Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

1 reference

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21 January 2018

Sample type bias in the analysis of cancer genomes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.280

21 January 2018

Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.280

21 January 2018

Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.280

21 January 2018

Glioblastoma stem-like cell lines with either maintenance or loss of high-level EGFR amplification, generated via modulation of ligand concentration.

1 reference

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21 January 2018

Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

1 reference

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21 January 2018

Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells

1 reference

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21 January 2018

Histone deacetylases and cancer: causes and therapies

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21 January 2018

Valproic Acid: second generation

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Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid

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21 January 2018

Grand rounds at the National Institutes of Health: HDAC inhibitors as radiation modifiers, from bench to clinic

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21 January 2018

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

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Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance

1 reference

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31 March 2020

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