(Q54376413)

29 May 2018

title

Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme. (English)

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29 May 2018

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Marie-Thérése Stockhausen

1

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29 May 2018

Helle Broholm

2

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29 May 2018

Mette Villingshøj

3

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29 May 2018

Maria Kirchhoff

4

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29 May 2018

Tommy Gerdes

5

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29 May 2018

Karina Kristoffersen

6

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29 May 2018

Michael Kosteljanetz

7

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29 May 2018

Mogens Spang-Thomsen

8

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29 May 2018

Hans Skovgaard Poulsen

9

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29 May 2018

language of work or name

English

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publication date

15 April 2011

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29 May 2018

Experimental Cell Research

published in

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29 May 2018

volume

317

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29 May 2018

page(s)

1513-1526

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29 May 2018

issue

11

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29 May 2018

Genetic pathways to primary and secondary glioblastoma

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

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Epidermal growth factor receptor mutation type III transfected into a small cell lung cancer cell line is predominantly localized at the cell surface and enhances the malignant phenotype

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Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility

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Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme

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Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII.

7 January 2021

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Constitutive EGFR signaling confers a motile phenotype to neural stem cells

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Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

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The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.

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Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: prognostic significance and relationship to other prognostic factors.

7 January 2021

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Clinical significance of EGFR amplification and the aberrant EGFRvIII transcript in conventionally treated astrocytic gliomas.

7 January 2021

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The natural history of EGFR and EGFRvIII in glioblastoma patients

7 January 2021

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Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.

7 January 2021

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Prognostic impact of molecular markers in a series of 220 primary glioblastomas.

7 January 2021

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Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme

7 January 2021

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Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance

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Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

7 January 2021

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Phase II trial of gefitinib in recurrent glioblastoma

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Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR

7 January 2021

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

7 January 2021

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Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

7 January 2021

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Identification of human brain tumour initiating cells

7 January 2021

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Isolation of cancer stem cells from adult glioblastoma multiforme

7 January 2021

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

7 January 2021

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Quantitation and gompertzian analysis of tumor growth

7 January 2021

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Automatic analysis of multiplex ligation-dependent probe amplification products (exemplified by a commercial kit for prenatal aneuploidy detection).

7 January 2021

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Evaluation of epidermal growth factor receptor (EGFR) by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) in archival gliomas using bright-field microscopy

7 January 2021

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Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

7 January 2021

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Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

7 January 2021

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Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

7 January 2021

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Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

7 January 2021

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Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma.

7 January 2021

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Amplification and differential expression of members of the erbB-gene family in human glioblastoma.

7 January 2021

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Deletion and tandem duplication of exons 2 - 7 in the epidermal growth factor receptor gene of a human malignant glioma

7 January 2021

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Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

7 January 2021

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Acquired rearrangement of an amplified epidermal growth factor receptor (EGFR) gene in a human glioblastoma xenograft

7 January 2021

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Oncogenic epidermal growth factor receptor mutants with tandem duplication: gene structure and effects on receptor function.

7 January 2021

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Tandem duplication of the epidermal growth factor receptor tyrosine kinase and calcium internalization domains in A-172 glioma cells

7 January 2021

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Amplified, overexpressed and rearranged epidermal growth factor receptor gene in a human astrocytoma cell line

7 January 2021

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Isolation, characterization, and use of stem cells from the CNS.

7 January 2021

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Stem cells in the central nervous system

7 January 2021

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Localization of epidermal growth factor receptors and putative neuroblasts in human subependymal zone.

7 January 2021

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A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2011.04.001

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2011.04.001

10.1016/J.YEXCR.2011.04.001

7 January 2021

Identifiers

DOI

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29 May 2018

PubMed ID

21514294

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29 May 2018