(Q39783570)

English

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells

scientific article published on 24 October 2009

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells (English)

1 reference

Europe PubMed Central

14 September 2017

neural stem cell

1 reference

based on heuristic

inferred from title

Angel Ayuso-Sacido

object named as

Angel Ayuso-Sacido

1

0 references

Donald M O'Rourke

object named as

Donald M O'Rourke

5

0 references

José M García-Verdugo

object named as

Jose Manuel García-Verdugo

7

0 references

6

object named as

Eric C Holland

1 reference

Europe PubMed Central

14 September 2017

author name string

Jennifer A Moliterno

2

1 reference

Europe PubMed Central

14 September 2017

Sebila Kratovac

3

1 reference

Europe PubMed Central

14 September 2017

Gurpreet S Kapoor

4

1 reference

Europe PubMed Central

14 September 2017

Neeta S Roy

8

1 reference

Europe PubMed Central

14 September 2017

John A Boockvar

9

1 reference

Europe PubMed Central

14 September 2017

publication date

24 October 2009

1 reference

Europe PubMed Central

14 September 2017

Journal of Neuro-Oncology

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Europe PubMed Central

14 September 2017

97

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Europe PubMed Central

14 September 2017

323-337

1 reference

Europe PubMed Central

14 September 2017

3

1 reference

Europe PubMed Central

14 September 2017

https://scigraph.springernature.com/pub.10.1007/s11060-009-0035-x

0 references

Oligodendrocytes and progenitors become progressively depleted within chronically demyelinated lesions

1 reference

https://api.crossref.org/works/10.1007%2FS11060-009-0035-X

21 January 2018

Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental changes in neural progenitor cell lineage commitment do not depend on epidermal growth factor receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host cis-mediated extinction of a retrovirus permissive for expression in embryonal stem cells during differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and clinical significance of pepsinogen C in uveal melanomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell types, lineage, and architecture of the germinal zone in the adult dentate gyrus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of EGFR amplification and the aberrant EGFRvIII transcript in conventionally treated astrocytic gliomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of cancer stem cells from adult glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain tumour stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of constitutively activated EGFRvIII in non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular pathogenesis of malignant gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse models of human cancer as tools in drug development.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The developmental biology of brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive EGFR signaling confers a motile phenotype to neural stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockdown of Stat3 in C17.2 neural stem cells facilitates the generation of neurons: a possibility of transplantation with a low level of oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the EGF receptor family members ErbB2, ErbB3, and ErbB4 in germinal zones of the developing brain and in neurosphere cultures containing CNS stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K-AKT pathway negatively controls EGFR-dependent DNA-binding activity of Stat3 in glioblastoma multiforme cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain-dependent epithelial defects in mice lacking the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative translational control of gene expression by Ras and Akt in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of long-range GABAergic connections distributed throughout the mouse neocortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radial glia give rise to adult neural stem cells in the subventricular zone

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19855928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-009-0035-X

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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