(Q40568043)

English

Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin

scientific article published on June 2004

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin (English)

1 reference

Europe PubMed Central

21 September 2017

author name string

Bin Li

1

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Europe PubMed Central

21 September 2017

Min Yuan

2

1 reference

Europe PubMed Central

21 September 2017

In-Ah Kim

3

1 reference

Europe PubMed Central

21 September 2017

Chi-Ming Chang

4

1 reference

Europe PubMed Central

21 September 2017

Eric J Bernhard

5

1 reference

Europe PubMed Central

21 September 2017

Hui-Kuo G Shu

6

1 reference

Europe PubMed Central

21 September 2017

language of work or name

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publication date

1 June 2004

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Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

23

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Europe PubMed Central

21 September 2017

4594-4602

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Europe PubMed Central

21 September 2017

26

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Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207602

0 references

Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells

1 reference

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21 January 2018

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

1 reference

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21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

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21 January 2018

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

21 January 2018

Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

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Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

Creation of human tumour cells with defined genetic elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207602

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207602

1 reference

Europe PubMed Central

21 September 2017

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1 reference

Europe PubMed Central

21 September 2017

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