(Q28115068)

3 January 2017

title

TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1 (English)

1 reference

Poly(ADP-ribose) polymerase 1

3 January 2017

main subject

1 reference

Tankyrase 1 binding protein 1

GOA release 2020-03-11

1 reference

cellular response to ionizing radiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Lian-Hong Zou

1

1 reference

3 January 2017

Zeng-Fu Shang

2

1 reference

3 January 2017

Wei Tan

3

1 reference

3 January 2017

Xiao-Dan Liu

4

1 reference

3 January 2017

Qin-Zhi Xu

5

1 reference

3 January 2017

Man Song

6

1 reference

3 January 2017

Yu Wang

7

1 reference

3 January 2017

Hua Guan

8

1 reference

3 January 2017

Shi-Meng Zhang

9

1 reference

3 January 2017

Lan Yu

10

1 reference

3 January 2017

Cai-Gao Zhong

11

1 reference

3 January 2017

Ping-Kun Zhou

12

1 reference

3 January 2017

language of work or name

English

0 references

publication date

30 March 2015

1 reference

3 January 2017

1 reference

3 January 2017

volume

6

1 reference

3 January 2017

issue

9

1 reference

3 January 2017

page(s)

7011–7022

1 reference

describes a project that uses

3 January 2017

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4466666/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)

20 March 2017

1 reference

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Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation

20 March 2017

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Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

20 March 2017

1 reference

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Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

20 March 2017

1 reference

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

20 March 2017

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20 March 2017

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20 March 2017

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Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

20 March 2017

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Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

20 March 2017

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A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

20 March 2017

1 reference

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Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner

20 March 2017

1 reference

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Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment

20 March 2017

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Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

20 March 2017

1 reference

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Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

20 March 2017

1 reference

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Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

29 September 2017

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Unraveling the complexities of DNA-dependent protein kinase autophosphorylation

29 September 2017

1 reference

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DNA-PKcs activates the Chk2-Brca1 pathway during mitosis to ensure chromosomal stability

29 September 2017

1 reference

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DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin

29 September 2017

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DNA double strand break repair via non-homologous end-joining

29 September 2017

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MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion

29 September 2017

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DAB2IP regulates autophagy in prostate cancer in response to combined treatment of radiation and a DNA-PKcs inhibitor

29 September 2017

1 reference

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Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition

29 September 2017

1 reference

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PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation.

29 September 2017

1 reference

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Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs

29 September 2017

1 reference

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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

29 September 2017

1 reference

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Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Initiating cellular stress responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Visualization of a DNA-PK/PARP1 complex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Poly(ADP-Ribose) polymerase-1 and DNA-dependent protein kinase have equivalent roles in double strand break repair following ionizing radiation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466666

[Expression of DNA-PK in hepato- and cholangio-neoplasms and its significance]

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25749521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.3137

0 references

PMC publication ID

4466666

0 references

1 reference