Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28115266)
Watch
English
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid
scientific journal article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
title
Crystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid
(English)
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
main subject
crystal structure
0 references
Aldehyde dehydrogenase 1 family member A3
1 reference
stated in
GOA release 2020-03-11
protein homotetramerization
1 reference
stated in
GOA release 2020-03-11
tretinoin
1 reference
based on heuristic
inferred from title
author
Silvia Garavaglia
series ordinal
6
0 references
Menico Rizzi
series ordinal
5
0 references
author name string
Andrea Moretti
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
Jianfeng Li
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
Stefano Donini
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
Robert W. Sobol
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
language of work or name
English
0 references
publication date
19 October 2016
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
published in
Scientific Reports
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
volume
6
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
page(s)
35710
1 reference
stated in
PubMed
PubMed ID
27759097
retrieved
3 January 2017
copyright license
Creative Commons Attribution 4.0 International
start time
19 October 2016
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Inference of macromolecular assemblies from crystalline state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
XDS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
ARP/wARP and molecular replacement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Structure validation by Calpha geometry: phi,psi and Cbeta deviation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Towards automated crystallographic structure refinement with phenix.refine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
The nuclear receptor superfamily: the second decade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Stem cells, cancer, and cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Free R value: a novel statistical quantity for assessing the accuracy of crystal structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Phasercrystallographic software
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Refinement of macromolecular structures by the maximum-likelihood method
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Features and development of Coot
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
The CCP4 suite: programs for protein crystallography
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
The so-called "testis-specific aldehyde dehydrogenase" corresponds to type 2 retinaldehyde dehydrogenase in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
A novel isoenzyme of aldehyde dehydrogenase specifically involved in the biosynthesis of 9-cis and all-trans retinoic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
20 March 2017
Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Crystallographic evidence for active-site dynamics in the hydrolytic aldehyde dehydrogenases. Implications for the deacylation step of the catalyzed reaction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Structural shifts of aldehyde dehydrogenase enzymes were instrumental for the early evolution of retinoid-dependent axial patterning in metazoans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Thermodynamic stability of carbonic anhydrase: measurements of binding affinity and stoichiometry using ThermoFluor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Human aldehyde dehydrogenases: potential pathological, pharmacological, and toxicological impact
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Genetic dissection of retinoid dehydrogenases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Human aldehyde dehydrogenase gene family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
29 September 2017
Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5069622
retrieved
2 June 2018
Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSREP35710
retrieved
21 January 2018
Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSREP35710
retrieved
21 January 2018
Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSREP35710
retrieved
21 January 2018
Possible role of liver cytosolic and mitochondrial aldehyde dehydrogenases in acetaldehyde metabolism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27759097
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27759097
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/SREP35710
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2913019
Dimensions Publication ID
1035435796
0 references
OpenCitations bibliographic resource ID
2913019
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2913019
PMCID
5069622
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2913019
PubMed ID
27759097
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2913019
Springer Nature article ID
10.1038/srep35710
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
