(Q28115339)

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures (English)

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

FMRP translational regulator 1

27 February 2020

main subject

1 reference

regulation of neuronal action potential

GOA release 2020-03-11

1 reference

Potassium large conductance calcium-activated channel, subfamily M, beta member 4

GOA release 2020-03-11

1 reference

disability affecting intellectual abilities

GOA release 2020-03-11

intellectual disability

1 reference

based on heuristic

inferred from title

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

8

Jeannie Visootsak

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Pan-Yue Deng

2

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Young Mi Oh

4

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Yongcheol Cho

5

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Valeria Cavalli

9

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Peng Jin

10

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Xiaodong Cheng

11

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Leila K Myrick

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Mickael J Poidevin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Joshua A Suhl

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Stephen T Warren

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Vitaly A Klyachko

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

English

0 references

publication date

5 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

27 February 2020

published in

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

112

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

4

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

949-956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein

27 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Altered synaptic plasticity in a mouse model of fragile X mental retardation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

The fragile X-cerebellum connection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X syndrome due to a missense mutation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Predicting the diagnosis of autism spectrum disorder using gene pathway analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Molecular mechanisms of fragile X syndrome: a twenty-year perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Targeting BK (big potassium) channels in epilepsy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A mouse model of the human Fragile X syndrome I304N mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Ca2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Deficit of Kcnma1 mRNA expression in the dentate gyrus of epileptic rats.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Calcium-activated potassium channels: multiple contributions to neuronal function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

A point mutation in the FMR-1 gene associated with fragile X mental retardation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313821

Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

FMRP acts as a key messenger for dopamine modulation in the forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Presynaptic FMR1 genotype influences the degree of synaptic connectivity in a mosaic mouse model of fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Tremorgenic mycotoxin intoxication with penitrem A and roquefortine in two dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1423094112

21 January 2018

Identifiers

DOI

10.1073/PNAS.1423094112

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

ADS bibcode

2015PNAS..112..949M

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25561520%20AND%20SRC:MED&resulttype=core&format=json