(Q28115713)

3 January 2017

title

Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase (English)

1 reference

tryptophan 2,3-dioxygenase

3 January 2017

main subject

1 reference

protein homotetramerization

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Farhad Forouhar

2

0 references

Maria Almira Correia

11

object named as

Maria Almira Correia

1 reference

3 January 2017

author name string

Ariel Lewis-Ballester

1

1 reference

3 January 2017

Sung-Mi Kim

3

1 reference

3 January 2017

Scott Lew

4

1 reference

3 January 2017

YongQiang Wang

5

1 reference

3 January 2017

Shay Karkashon

6

1 reference

3 January 2017

Jayaraman Seetharaman

7

1 reference

3 January 2017

Dipanwita Batabyal

8

1 reference

3 January 2017

Bing-Yu Chiang

9

1 reference

3 January 2017

Munif Hussain

10

1 reference

3 January 2017

Syun-Ru Yeh

12

1 reference

3 January 2017

Liang Tong

13

1 reference

3 January 2017

language of work or name

English

0 references

publication date

20 October 2016

1 reference

3 January 2017

1 reference

3 January 2017

volume

6

1 reference

3 January 2017

page(s)

35169

1 reference

Creative Commons Attribution 4.0 International

3 January 2017

copyright license

start time

20 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis

20 March 2017

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Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding

20 March 2017

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Crystal structure of Drosophila melanogaster tryptophan 2,3-dioxygenase reveals insights into substrate recognition and catalytic mechanism

20 March 2017

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20 March 2017

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Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase

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The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease

20 March 2017

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Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination

20 March 2017

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Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism

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Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway

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Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors

29 September 2017

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29 September 2017

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Human liver cytochrome P450 3A4 ubiquitination: molecular recognition by UBC7-gp78 autocrine motility factor receptor and UbcH5a-CHIP-Hsc70-Hsp40 E2-E3 ubiquitin ligase complexes

29 September 2017

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Tryptophan-catabolizing enzymes - party of three

29 September 2017

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Heme enzyme structure and function

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Complete reaction mechanism of indoleamine 2,3-dioxygenase as revealed by QM/MM simulations.

29 September 2017

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Indoleamine 2,3-dioxygenase expression in human cancers: clinical and immunologic perspectives

29 September 2017

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The mechanism of formation of N-formylkynurenine by heme dioxygenases.

29 September 2017

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Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases

29 September 2017

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29 September 2017

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EPR and Mössbauer spectroscopy show inequivalent hemes in tryptophan dioxygenase

29 September 2017

1 reference

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Evidence for a ferryl intermediate in a heme-based dioxygenase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Density functional theory study on a missing piece in understanding of heme chemistry: the reaction mechanism for indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Human tryptophan dioxygenase: a comparison to indoleamine 2,3-dioxygenase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Heme-Containing Oxygenases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Harmonic and anharmonic dynamics of Fe-CO and Fe-O(2) in heme models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

My life with tryptophan--never a dull moment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Control of enzyme levels in animal tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Molecular characterization of the Drosophila vermilion locus and its suppressible alleles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

Substrate-protein interaction in human tryptophan dioxygenase: the critical role of H76.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071832

ONIOM study on a missing piece in our understanding of heme chemistry: bacterial tryptophan 2,3-dioxygenase with dual oxidants.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP35169

Initial O₂ Insertion Step of the Tryptophan Dioxygenase Reaction Proposed by a Heme-Modification Study

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27762317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP35169

1 reference

Dimensions Publication ID

1004582918

0 references

1 reference

1 reference

1 reference