(Q28115730)

English

Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production

scientific journal article

In more languages

Statements

scholarly article

1 reference

3 January 2017

Leptin enhances synthesis of proinflammatory mediators in human osteoarthritic cartilage--mediator role of NO in leptin-induced PGE2, IL-6, and IL-8 production (English)

1 reference

3 January 2017

0 references

nitric oxide synthase 2

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

regulation of cytokine production involved in inflammatory response

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Katriina Vuolteenaho

object named as

Katriina Vuolteenaho

1

1 reference

ORCID Public Data File 2021

author name string

Anna Koskinen

2

1 reference

3 January 2017

Meiju Kukkonen

3

1 reference

3 January 2017

Riina Nieminen

4

1 reference

3 January 2017

Unto Päivärinta

5

1 reference

3 January 2017

Teemu Moilanen

6

1 reference

3 January 2017

Eeva Moilanen

7

1 reference

3 January 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 January 2009

1 reference

3 January 2017

Mediators of Inflammation

1 reference

3 January 2017

2009

1 reference

3 January 2017

345838

1 reference

3 January 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

Leptin in gastroprotection induced by cholecystokinin or by a meal. Role of vagal and sensory nerves and nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

20 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

7 April 2017

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

7 April 2017

Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

The role of nitric oxide in osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Role of leptin in immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Leptin induces nitric oxide synthase type II in C6 glioma cells. Role for nuclear factor-kappaB in hormone effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Intracellular signalling pathways activated by leptin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Leptin in immunology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

The role of cytokines in cartilage matrix degeneration in osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Cytokines as therapeutic targets for osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Evidence for a key role of leptin in osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Effects of leptin on the production of cytokines by cultured human endometrial stromal and epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Synergistic induction of nitric oxide synthase type II: in vitro effect of leptin and interferon-gamma in human chondrocytes and ATDC5 chondrogenic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Leptin potentiates IFN-gamma-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Leptin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Human articular chondrocytes express functional leptin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Human leptin stimulates proliferation and activation of human circulating monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

29 September 2017

Nitric oxide mediates interleukin-1 induced inhibition of glycosaminoglycan synthesis in rat articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Nitric oxide mediates leptin-induced luteinizing hormone-releasing hormone (LHRH) and LHRH and leptin-induced LH release from the pituitary gland.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Chondrocyte apoptosis induced by nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

2 June 2018

Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Regulation of nitric oxide production in osteoarthritic and rheumatoid cartilage. Role of endogenous IL-1 inhibitors

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Animal models of arthritis in NOS2-deficient mice.

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Leptin-induced nitric oxide production in white adipocytes is mediated through PKA and MAP kinase activation

1 reference

https://api.crossref.org/works/10.1155%2F2009%2F345838

21 January 2018

Selective iNOS inhibitor 1400W enhances anti-catabolic IL-10 and reduces destructive MMP-10 in OA cartilage. Survey of the effects of 1400W on inflammatory mediators produced by OA cartilage as detected by protein antibody array.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

27 November 2018

Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

27 November 2018

Nitric-Oxide Mediates Suppression of Cartilage Proteoglycan Synthesis by Interleukin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726438

27 November 2018

Systemic and local regulation of articular cartilage metabolism: Where does leptin fit in the puzzle?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil accumulation and activation by homologous IL-8 in rabbits. IL-8 induces destruction of cartilage and production of IL-1 and IL-1 receptor antagonist in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal role of nitric oxide in the control of blood pressure after leptin administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Inhibitory Effect of Leptin on Angiotensin II-Induced Vasoconstriction in Vascular Smooth Muscle Cells Is Mediated via a Nitric Oxide-Dependent Mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritis or osteoarthrosis: the definition of inflammation becomes a semantic issue in the genomic era of molecular medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and interleukin-8 levels in serum and synovial fluid of patients with osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and proteoglycan biosynthesis by human articular chondrocytes in alginate culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum leptin levels correlate with interleukin-6 levels and disease activity in patients with ankylosing spondylitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide activates metalloprotease enzymes in articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin Promotes Differentiation and Survival of Human Dendritic Cells and Licenses Them for Th1 Priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of inducible nitric oxide synthase reduces progression of experimental osteoarthritis in vivo: possible link with the reduction in chondrocyte apoptosis and caspase 3 level

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19688109

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2009/345838

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28115730&oldid=1832531581"